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MAK085

Sigma-Aldrich

Lipid Peroxidation (MDA) Assay Kit

sufficient for 100 colorimetric or fluorometric tests

Sinonimo/i:

MDA Assay, TBARS Assay, Thiobarbituric Acid Reactive Substances Assay

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About This Item

Codice UNSPSC:
12161503
NACRES:
NA.84

impiego

sufficient for 100 colorimetric or fluorometric tests

Controllo stupefacenti

regulated under CDSA - not available from Sigma-Aldrich Canada

Metodo di rivelazione

colorimetric
fluorometric

Malattie correlate

endocrinological disorders, diabetes; neurological disorders; cancer; cardiovascular diseases

Temperatura di conservazione

−20°C

Descrizione generale

Lipid peroxidation is the degradation of lipids that occurs as a result of oxidative damage and is a useful marker for oxidative stress. Polyunsaturated lipids are susceptible to an oxidative attack, typically by reactive oxygen species, resulting in a well-defined chain reaction with the production of end products such as malondialdehyde (MDA). Lipid peroxidation may contribute to the pathology of many diseases including atherosclerosis, diabetes, and Alzheimer′s.

Applicazioni

Lipid peroxidation (MDA) assay kit has been used to determine the levels of malondialdehyde (MDA).

Compatibilità

Suitable for the measurement of malondialdehyde (MDA) in a variety of samples including tissue, cells and plasma

Principio

In this kit, lipid peroxidation is determined by the reaction of MDA with thiobarbituric acid (TBA) to form a colorimetric (532 nm)/fluorometric (λex = 532/λem = 553 nm) product, proportional to the MDA present.

Prodotti correlati

N° Catalogo
Descrizione
Determinazione del prezzo

92210

Timestrip Plus™ 0 °C

Avvertenze

Danger

Indicazioni di pericolo

H225 - H302 - H314 - H411

Classi di pericolo

Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Dam. 1 - Flam. Liq. 2 - Skin Corr. 1C

Codice della classe di stoccaggio

3 - Flammable liquids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

57.2 °F - closed cup

Punto d’infiammabilità (°C)

14 °C - closed cup

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Yasemin Yuksel et al.
Journal of investigative surgery : the official journal of the Academy of Surgical Research, 29(6), 389-398 (2016-05-05)
The purpose of this study was to evaluate the possible protective/therapeutic effects of aloe vera (AV) on ischemia-reperfusion injury (I/R) of spinal cord in rats. A total of 28 Wistar Albino rats were divided into four random groups of equal
Maria I Ayuso et al.
ACS chemical neuroscience, 8(10), 2202-2213 (2017-07-22)
There is a need to develop additional effective therapies for ischemic stroke. Nitrones, which were first developed as reactive oxygen species (ROS)-trapping compounds, have been proposed as neuroprotective agents for ischemic stroke, a ROS-related disorder. The previous reported ROS-trapping compound
Erdem Kamil Ozer et al.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 86, 583-589 (2016-12-27)
The cyclooxygenase (COX)-2 overexpression is associated with vascular injury and multiple organ failure in sepsis. However, constitutive COX-1 and basal COX-2 expressions have physiological effects. We aimed to investigate the effects of partial and selective COX-2 inhibition without affecting constitutive
Heon Woo Lee et al.
Scientific reports, 8(1), 11595-11595 (2018-08-04)
To mitigate cyanobacterial blooms, the naphthoquinone derivative, NQ 2-0, which has selective algicidal activity against cyanobacteria, has been developed. However, due to a lack of information on its algicidal mechanisms, there are significant gaps in our understanding of how this
Erdem Kamil Ozer et al.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 91, 912-919 (2017-05-16)
Coenzyme Q10 (CoQ10) is a naturally occurring, lipid-soluble antioxidant and an essential electron carrier in the mitochondrial respiratory chain. In sepsis, CoQ10 deficiency induced by mitochondrial failure can lead to hypoxia, hypoperfusion, oxidative organ damage and finally death. We aimed
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