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Key Documents

Altri documenti

M1796

Sigma-Aldrich

(±)-3,4-Methylenedioxy-N-­ethyl­amphetamine hydrochloride

≥98% (TLC)

Sinonimo/i:

MDEA hydrochloride, N-Ethyl-3,4-MDA hydrochloride

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About This Item

Formula empirica (notazione di Hill):
C12H17NO2 · HCl
Numero CAS:
74341-78-9
Peso molecolare:
243.73
Numero MDL:
MFCD01659568
Codice UNSPSC:
12352116
ID PubChem:
24896694

Livello qualitativo

200

Saggio

≥98% (TLC)

Controllo stupefacenti

USDEA Schedule I; Home Office Schedule 1; stupéfiant (France); kontrollierte Droge in Deutschland; regulated under CDSA - not available from Sigma-Aldrich Canada; psicótropo (Spain); Decreto Lei 15/93: Tabela IA (Portugal)

Stringa SMILE

Cl[H].NCCc1ccc2OCOc2c1

InChI

1S/C12H17NO2.ClH/c1-3-13-9(2)6-10-4-5-11-12(7-10)15-8-14-11;/h4-5,7,9,13H,3,6,8H2,1-2H3;1H
IBDIPBWIXJRJQM-UHFFFAOYSA-N

Azioni biochim/fisiol

Psychotropic compound causing a reduction in serotonin level and in tryptophan hydroxylase activity in the brain. May cause structural damage to serotonenergic neurons.

Altre note

CAS# 116861-63-3, which was listed previously, is for histidine-copper complex.

Pittogrammi

Skull and crossbones
GHS06

Avvertenze

Danger

Indicazioni di pericolo

H301 - H336

Classi di pericolo

Acute Tox. 3 Oral - STOT SE 3

Organi bersaglio

Respiratory system

Codice della classe di stoccaggio

6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

Classe di pericolosità dell'acqua (WGK)

WGK 2

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges

Certificati d'analisi (COA)

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M Johnson et al.
Biochemical pharmacology, 38(23), 4333-4338 (1989-12-01)
The effect of N-ethyl-3,4-methylenedioxyamphetamine (MDE) on the central serotonergic system was studied. Within 1 hr after administration of MDE (10 mg/kg), the concentration of 5-hydroxytryptamine (5-HT) and the activity of tryptophan hydroxylase (TPH) had declined significantly in the hippocampus but
H G Series et al.
Experimental neurology, 128(1), 50-58 (1994-07-01)
N-ethyl-3,4-methylenedioxyamphetamine (MDE) is one of a group of substituted amphetamines which have effects on several serotonergic markers such as tissue levels of serotonin and activity of tryptophan hydroxylase. In this study we have compared its effects on the rat brain
Jin Young Kim et al.
Archives of pharmacal research, 31(12), 1644-1651 (2008-12-23)
A liquid chromatography-electrospray ionization-tandem mass spectrometric (LC-ESI-MS/MS) method was developed and validated for the simultaneous detection and quantification of seven amphetamine derivatives (amphetamine (AP), methamphetamine (MA), 3,4-methylenedioxy-N-amphetamine (MDA), 3,4-methylenedioxy-N-methamphetamine (MDMA), 3,4-methylenedioxy-N-ethylamphetamine (MDEA), N,N-dimethylamphetamine (DMA), and N,N-dimethylamphetamine-N-oxide (DMANO)) in human urine.
Tamer Awad et al.
Journal of chromatographic science, 48(9), 726-732 (2010-09-30)
Three regioisomeric 3,4-methylenedioxyphenethylamines having the same molecular weight and major mass spectral fragments of equal mass have been reported as drugs of abuse in forensic studies in recent years. These compounds are 3,4-methylenedioxy-N-ethylamphetamine (MDEA), 3,4-methylenedioxy-N,N-dimethylamphetamine (MDMMA), and N-methyl-1-(3,4-methylenedioxyphenyl)-2-butanamine (MBDB). A
R W Romberg et al.
Journal of analytical toxicology, 35(1), 15-22 (2011-01-12)
This study evaluated the potential for partial separation of drugs from their deuterated internal standards using Cerex(®) Polycrom™ CLIN II solid-phase extraction (SPE) cartridges. After elution from the column and derivatization, gas chromatography-mass spectrometry results showed that the target compound
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