M0880

Ethyl methanesulfonate

liquid

• Sinonimo/i: Ethyl mesylate, Methanesulfonic acid ethyl ester
• Formula condensata: CH₃SO₃CH₂CH₃
• Numero CAS: 62-50-0
• Peso molecolare: 124.16
• Beilstein: 773969
• Numero CE: 200-536-7
• Numero MDL: MFCD00007559
• Codice UNSPSC: 12352108
• ID PubChem: 24896575
• NACRES: NA.25

Proprietà

• Forma fisica: liquid
• Indice di rifrazione: n20/D 1.418 (lit.)
• P. eboll.: 85-86 °C/10 mmHg (lit.)
• Densità: 1.206 g/mL at 20 °C
• Stringa SMILE: CCOS(C)(=O)=O
• InChI: 1S/C3H8O3S/c1-3-6-7(2,4)5/h3H2,1-2H3; PLUBXMRUUVWRLT-UHFFFAOYSA-N

Descrizione

Applicazioni

Ethyl methanesulfonate had been used for inducing mutation in mouse embryonic fibroblasts, yeast human embryonic kidney cell lines and human lymphocytes.

Azioni biochim/fisiol

Ethyl methanesulfonate is a DNA ethylating agent, mutagenic to plants and animals and carcinogenic in mammals. It has been used as a model alkylating agent in studies of DNA repair processes. EMS induces base substitutions of guanine-cytosine (G/C) to adenine-thymine (A/T). EMS also generates point mutations and single nucleotide polymorphisms in genomes. EMS is potential chemical mutagen used for inducing mutation in rice, wheat and Arabidopsis thaliana.

Informazioni sulla sicurezza

• Pittogrammi: GHS08,GHS07
• Avvertenze: Danger
• Indicazioni di pericolo: H302,H315,H317,H319,H340,H350,H361f
• Consigli di prudenza: P202 - P280 - P301 + P312 - P302 + P352 - P305 + P351 + P338 - P308 + P313
• Classi di pericolo: Acute Tox. 4 Oral - Carc. 1B - Eye Irrit. 2 - Muta. 1B - Repr. 2 - Skin Irrit. 2 - Skin Sens. 1
• Codice della classe di stoccaggio: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• Classe di pericolosità dell'acqua (WGK): WGK 3
• Punto d’infiammabilità (°F): 212.0 °F
• Punto d’infiammabilità (°C): 100 °C
• Dispositivi di protezione individuale: Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter