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Key Documents

L2659

Sigma-Aldrich

Lauroyl coenzyme A lithium salt

≥90% (HPLC)

Sinonimo/i:

C12-CoA, Dodecanoyl-Coenzyme A lithium salt

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About This Item

Formula condensata:
C33H58N7O17P3S
Numero CAS:
Peso molecolare:
955.77
Numero MDL:
Codice UNSPSC:
41106305
ID PubChem:
NACRES:
NA.51

Livello qualitativo

Saggio

≥90% (HPLC)

Temperatura di conservazione

−20°C

Stringa SMILE

[Li+].CCCCCCCCCCCC(=O)SCCNC(=O)CCNC(=O)[C@H](O)C(C)(C)COP([O-])(=O)OP(O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1OP(O)(O)=O)n2cnc3c(N)ncnc23

InChI

1S/C33H58N7O17P3S.Li/c1-4-5-6-7-8-9-10-11-12-13-24(42)61-17-16-35-23(41)14-15-36-31(45)28(44)33(2,3)19-54-60(51,52)57-59(49,50)53-18-22-27(56-58(46,47)48)26(43)32(55-22)40-21-39-25-29(34)37-20-38-30(25)40;/h20-22,26-28,32,43-44H,4-19H2,1-3H3,(H,35,41)(H,36,45)(H,49,50)(H,51,52)(H2,34,37,38)(H2,46,47,48);/q;+1/p-1/t22-,26-,27-,28+,32-;/m1./s1
FWNUZMNRIPYTPZ-CDSRRKEDSA-M

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Applicazioni

Lauroyl coenzyme A lithium salt has been used in the coenzyme A (CoA)-dependent acyltransferase assay to test the functionality of DRL1 protein. It is suitable for use as a standard to analyse the reaction product of lauric acid with firefly luciferase.

Azioni biochim/fisiol

Coenzyme A functions as an acyl group carrier, acetyl-CoA. Dodecanoyl-Coenzyme A (C12-CoA), a long-chain (C-12) saturated fatty acyl-CoA, is used as an intermediate in lipid metabolism and is involved in lipid biosynthesis and fatty acid transport.. Lauroyl CoA is a substrate for FAM34A proteins and a product of firefly luciferase.

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

Eyeshields, Gloves, type N95 (US)


Certificati d'analisi (COA)

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Faik Musayev et al.
Journal of molecular biology, 346(5), 1313-1321 (2005-02-17)
Beta-ketoacyl-acyl carrier protein synthase III (FabH) catalyzes a two step reaction that initiates the pathway of fatty acid biosynthesis in plants and bacteria. In Mycobacterium tuberculosis, FabH catalyzes extension of lauroyl, myristoyl and palmitoyl groups from which cell wall mycolic
Homeostasis of brassinosteroids regulated by DRL1, a putative acyltransferase in Arabidopsis
Zhu W, et al.
Molecular plant, 6(2), 546-558 (2013)
Yuichi Oba et al.
Bioscience, biotechnology, and biochemistry, 69(4), 819-828 (2005-04-26)
Recently we found that firefly luciferase is a bifunctional enzyme, catalyzing not only the luminescence reaction but also long-chain fatty acyl-CoA synthesis. Further, the gene product of CG6178 (CG6178), an ortholog of firefly luciferase in Drosophila melanogaster, was found to
Enzymatic and genetic characterization of firefly luciferase and Drosophila CG6178 as a fatty acyl-CoA synthetase
Oba Y, et al.
Bioscience, Biotechnology, and Biochemistry, 69(4), 819-828 (2005)
Li-Guo Hong et al.
Biotechnology letters, 41(4-5), 591-604 (2019-03-22)
We aimed to characterize a novel SGNH (Ser-Gly-Asn-His) family hydrolase from the annotated genome of marine bacteria with new features. A novel esterase Ali5 from Altererythrobacter ishigakiensis has been identified and classified into SGNH family. Ali5 presented a novel GNSL

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