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Key Documents

L2398

Sigma-Aldrich

Lactobionic acid

≥97% (TLC), cell impermeant agent

Sinonimo/i:

4-O-β-D-Galactopyranosyl-D-gluconic acid

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About This Item

Formula empirica (notazione di Hill):
C12H22O12
Numero CAS:
Peso molecolare:
358.30
Beilstein:
95054
Numero CE:
Numero MDL:
Codice UNSPSC:
12352201
ID PubChem:
NACRES:
NA.25

Origine biologica

synthetic (organic

Organic)

Livello qualitativo

Saggio

≥97% (TLC)

Forma fisica

powder

Colore

white

Punto di fusione

113-118 °C (lit.)

Solubilità

water: 50 mg/mL, clear, colorless

Temperatura di conservazione

room temp

Stringa SMILE

OC[C@@H](O)[C@@H](O[C@@H]1O[C@H](CO)[C@H](O)[C@H](O)[C@H]1O)[C@H](O)[C@@H](O)C(O)=O

InChI

1S/C12H22O12/c13-1-3(15)10(7(18)8(19)11(21)22)24-12-9(20)6(17)5(16)4(2-14)23-12/h3-10,12-20H,1-2H2,(H,21,22)/t3-,4-,5+,6+,7-,8-,9-,10-,12+/m1/s1
JYTUSYBCFIZPBE-AMTLMPIISA-N

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Categorie correlate

Descrizione generale

Lactobionic acid, a derivative of lactose, is an aldonic acid obtained from gluconic acid and galactose. It is a potential chelating agent, preservative and a prebiotic.

Applicazioni

Cell impermeant agent used for organ preservation
Lactobionic acid has been used as a control for the chemical characterization of the lactobionic acid produced by Zymomonas mobilis.

Azioni biochim/fisiol

Lactobionic acid has a role as an antioxidant and stabilizer-gelling agent. It is used as an ingredient in foods and pharmaceutical products.
Reported to inhibit production of hydroxyl radicals. Cryptic inhibitor of matrix metalloproteinases (MMP). Resistant to dietary metabolism but stimulates intestinal calcium absorption in rat.

Altre note

To gain a comprehensive understanding of our extensive range of Disaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 1

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

Eyeshields, Gloves, type N95 (US)


Certificati d'analisi (COA)

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D-(+)-Glucosio 97.5-102.0% anhydrous basis, meets EP, BP, JP, USP testing specifications

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J A Wahlberg et al.
Transplantation, 43(1), 5-8 (1987-01-01)
A new flushout solution for preservation of the pancreas was tested in the dog model of segmental pancreas autotransplantation. The solution osmolality was 320 mOsm/L, K+ = 120 mM, Na+ = 30 mM, and it contained the anion, lactobionate, and
Lactobionic acid produced by Zymomonas mobilis: alternative to prepare targeted nanoparticles
Valle TA, et al.
Pharmaceutica Analytica Acta, 4, 1-5 (2013)
Lactobionic acid: a high value-added lactose derivative for food and pharmaceutical applications
International dairy journal, 26(2), 103-111 (2012)
J H Southard et al.
Annual review of medicine, 46, 235-247 (1995-01-01)
Organ preservation is the supply line for organ transplantation. Currently, the liver, pancreas, and kidney can be successfully preserved for up to two days by flushing the organs with the University of Wisconsin (UW) organ preservation solution and storing them
C Charloux et al.
Free radical biology & medicine, 19(5), 699-704 (1995-11-01)
Superoxide and hydroxyl free radicals are strongly implicated in the deleterious effects of reperfusion of grafted organs. Iron ions are critical in the Fenton-like reaction that generates oxygen-free radicals from H2O2. Using the ADP/Fe2+/H2O2 .OH-generating system, we demonstrated that components

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