L090000

Diclorometano

• Sinonimo/i: Cloruro di metilene
• Formula empirica (notazione di Hill): CH₂Cl₂
• Numero CAS: 75-09-2
• Peso molecolare: 84.93
• Beilstein: 1730800
• Numero CE: 200-838-9
• Numero MDL: MFCD00000881
• Codice UNSPSC: 12352200
• ID PubChem: 329817376
• NACRES: NA.21

Proprietà

• Densità del vapore: 2.9 (vs air)
• Livello qualitativo: 200
• Tensione di vapore: 24.45 psi ( 55 °C); 6.83 psi ( 20 °C)
• Tipo: for DNA synthesis
• Nome Commerciale: Proligo Reagents
• Forma fisica: liquid
• Temp. autoaccensione: 1223 °F
• contiene: amylene as stabilizer
• Limite di esplosione: 22 %
• Condizioni di stoccaggio: dry at room temperature
• Impurezze: ≤50 ppm water content (Karl Fischer)
• Colore: clear
• Indice di rifrazione: n/D 1.421-1.425; n20/D 1.424 (lit.)
• P. eboll.: 39.8-40 °C (lit.)
• Punto di fusione: −95 °C (lit.)
• Densità: 1.325 g/mL at 25 °C (lit.)
• Stringa SMILE: ClCCl
• InChI: 1S/CH2Cl2/c2-1-3/h1H2; YMWUJEATGCHHMB-UHFFFAOYSA-N

Descrizione

Descrizione generale

In the solid-phase synthesis of oligonucleotides, liquid reagents are used in each step of the synthesis cycle. Overall synthesis performance, and therefore total product yield and purity of the crude oligonucleotide, is highly dependent on the chemical purity of the monomers and the supporting liquid reagents and other solvents like ethylacetate, dichloromethane, and dimethylformadine .Dichloromethane is an ordinary organic solvent frequently utilized in peptide synthesis. Under normal circumstances, DCM maintains highly stable and will not cause significant side reactions in peptide synthesis. It is a chlorinated organic solvent that is susceptible to degradation with time. This can be suppressed by adding amylene as a stabilizer.Dichloromethane has been tested as a solvent medium for the dipyridine-chromium(VI) oxide. Solubility was reported to be 12.5g/100ml. The role of the quantity of TiO2 loading on activated carbon support employed in the photodecomposition of dichloromethane has been investigated.

Applicazioni

Dichloromethane may be used as a solvent for the preparation of stock solutions of carotenoids. It may be employed as a solvent in the synthesis of polylactide-based (PLA) thin films. IT is also suitable as a solvent for the oxidation of primary and secondary alcohols using dipyridine-chromium(VI) oxide.

Informazioni sulla sicurezza

• Pittogrammi: GHS07,GHS08
• Avvertenze: Warning
• Indicazioni di pericolo: H315 - H319 - H336 - H351
• Consigli di prudenza: P202 - P261 - P264 - P302 + P352 - P305 + P351 + P338 - P308 + P313
• Classi di pericolo: Carc. 2 - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Organi bersaglio: Central nervous system
• Codice della classe di stoccaggio: 6.1D - Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
• Classe di pericolosità dell'acqua (WGK): WGK 2
• Punto d’infiammabilità (°F): does not flash
• Punto d’infiammabilità (°C): does not flash