I5281
L-Isoleucine
Produzione farmaceutica
Sinonimo/i:
(2S,3S)-2-Amino-3-methylpentanoic acid
Autenticatiper visualizzare i prezzi riservati alla tua organizzazione & contrattuali
About This Item
Formula condensata:
C2H5CH(CH3)CH(NH2)CO2H
Numero CAS:
Peso molecolare:
131.17
Beilstein:
1721792
Numero CE:
Numero MDL:
Codice UNSPSC:
12352209
eCl@ss:
32160406
NACRES:
NA.26
Prodotti consigliati
Origine biologica
non-animal source
Livello qualitativo
Saggio
≥98.5%
Forma fisica
crystalline powder
tecniche
cell culture | mammalian: suitable
Impurezze
endotoxin, heavy metals, residual solvents, tested
Punto di fusione
288 °C (dec.) (lit.)
Solubilità
1 M HCl: 50 mg/mL
applicazioni
pharmaceutical (small molecule)
Attività estranea
cytotoxicity, tested
Stringa SMILE
CC[C@H](C)[C@H](N)C(O)=O
InChI
1S/C6H13NO2/c1-3-4(2)5(7)6(8)9/h4-5H,3,7H2,1-2H3,(H,8,9)/t4-,5-/m0/s1
AGPKZVBTJJNPAG-WHFBIAKZSA-N
Cerchi prodotti simili? Visita Guida al confronto tra prodotti
Descrizione generale
Our SAFC® portfolio of high-quality raw materials for use in biopharmaceutical processing withstands strict quality control procedures plus the documentation and expertise to help our customers meet requirements as defined by the M-Clarity Program.
M-Clarity Program
Our comprehensive portfolio of upstream process chemicals not only provides biopharmaceutical manufacturers with high-quality raw materials for production of classical and novel therapies, but also helps them get to market faster and simplify regulatory challenges. Trust us to deliver supply chain transparency and reliable sourcing around the globe, streamlining your product qualification with best-in-class regulatory support and service.
M-Clarity Program
Our comprehensive portfolio of upstream process chemicals not only provides biopharmaceutical manufacturers with high-quality raw materials for production of classical and novel therapies, but also helps them get to market faster and simplify regulatory challenges. Trust us to deliver supply chain transparency and reliable sourcing around the globe, streamlining your product qualification with best-in-class regulatory support and service.
To request documentation for this product, please contact Customer Support and select ‘Product Documentation′. Please note that access to the documentation for this product requires a confidentiality disclosure agreement.
Applicazioni
L-Isoleucine is an essential amino acid. It can be biosynthesized from threonine or through fermentation of carbohydrates. The amino acid L-isoleucine is an isomer of L-Leucine, differing in the position of the side chain. It is also considered to be a branched chain amino acid, along with L-Leucine and L-Valine, which are sources of fuel and/or transport during cell development. It is used as a cell culture media component in the commercial biomanufacture of therapeutic recombinant proteins and monoclonal antibodies.
Note legali
SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany
Applicazioni
N° Catalogo
Descrizione
Determinazione del prezzo
Codice della classe di stoccaggio
11 - Combustible Solids
Classe di pericolosità dell'acqua (WGK)
WGK 1
Punto d’infiammabilità (°F)
Not applicable
Punto d’infiammabilità (°C)
Not applicable
Dispositivi di protezione individuale
Eyeshields, Gloves, type N95 (US)
Certificati d'analisi (COA)
Cerca il Certificati d'analisi (COA) digitando il numero di lotto/batch corrispondente. I numeri di lotto o di batch sono stampati sull'etichetta dei prodotti dopo la parola ‘Lotto’ o ‘Batch’.
Possiedi già questo prodotto?
I documenti relativi ai prodotti acquistati recentemente sono disponibili nell’Archivio dei documenti.
I clienti hanno visto anche
Eva Blomstrand et al.
The Journal of nutrition, 136(1 Suppl), 269S-273S (2005-12-21)
BCAAs (leucine, isoleucine, and valine), particularly leucine, have anabolic effects on protein metabolism by increasing the rate of protein synthesis and decreasing the rate of protein degradation in resting human muscle. Also, during recovery from endurance exercise, BCAAs were found
L Edvinsson
Blood vessels, 28(1-3), 35-45 (1991-01-01)
The cerebral circulation is supplied with two vasodilator systems: the parasympathetic system storing vasoactive intestinal peptide, peptide histidine isoleucine, acetylcholine and in a subpopulation of nerves neuropeptide Y, and the sensory system, mainly originating in the trigeminal ganglion, storing substance
Urho M Kujala et al.
Circulation, 127(3), 340-348 (2012-12-22)
Long-term physical inactivity seems to cause many health problems. We studied whether persistent physical activity compared with inactivity has a global effect on serum metabolome toward reduced cardiometabolic disease risk. Sixteen same-sex twin pairs (mean age, 60 years) were selected
Toshihiro Sato et al.
The Journal of biological chemistry, 278(6), 4314-4321 (2002-11-22)
Previously, we determined the crystal structures of the dimeric ligand binding region of the metabotropic glutamate receptor subtype 1. Each protomer binds l-glutamate within the crevice between the LB1 and LB2 domains. We proposed that the two different conformations of
Anna L Vestergaard et al.
Proceedings of the National Academy of Sciences of the United States of America, 111(14), E1334-E1343 (2014-04-08)
P4-ATPases (flippases) translocate specific phospholipids such as phosphatidylserine from the exoplasmic leaflet of the cell membrane to the cytosolic leaflet, upholding an essential membrane asymmetry. The mechanism of flipping this giant substrate has remained an enigma. We have investigated the
Chromatograms
application for HPLCIl team dei nostri ricercatori vanta grande esperienza in tutte le aree della ricerca quali Life Science, scienza dei materiali, sintesi chimica, cromatografia, discipline analitiche, ecc..
Contatta l'Assistenza Tecnica.