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H8636

Sigma-Aldrich

Anti-Haptoglobin antibody produced in rabbit

IgG fraction of antiserum, lyophilized powder

Sinonimo/i:

Anti-BP, Anti-HP2ALPHA2, Anti-HPA1S

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About This Item

Numero MDL:
Codice UNSPSC:
12352203
NACRES:
NA.46

Origine biologica

rabbit

Livello qualitativo

Coniugato

unconjugated

Forma dell’anticorpo

IgG fraction of antiserum

Tipo di anticorpo

primary antibodies

Clone

polyclonal

Stato

lyophilized powder

Reattività contro le specie

human

Confezionamento

vial of 2 mL lyophilized antiserum

tecniche

indirect ELISA: 1:30,000

N° accesso UniProt

applicazioni

research pathology

Temperatura di conservazione

2-8°C

modifica post-traduzionali bersaglio

unmodified

Informazioni sul gene

human ... HP(3240)

Descrizione generale

Haptoglobin (HP) is encoded by the gene mapped to human chromosome 16q22.2. There are two splice variants of the gene namely, HP1 and HP2.

Immunogeno

Human haptoglobin

Applicazioni

Anti-Haptoglobin antibody is suitable for use in Ouchterlony double diffusion (1:16) and immunoelectrophoresis.
Anti-Haptoglobin antibody produced in rabbit has been used in immunohistochemistry and western blotting.

Azioni biochim/fisiol

Haptoglobin is an antioxidant protein that binds with hemoglobin. Haptoglobin primarily functions to inhibit oxidative damage induced by hemoglobin. Alterations in haptoglobin have been associated with the risk of diabetic vascular disorders such as retinopathy, nephropathy and cardiovascular diseases . Anti-Haptoglobin antibody is specific for haptoglobin in humans.

Stato fisico

Lyophilized from 0.01 M phosphate buffered saline, pH 7.2

Ricostituzione

Reconstitute with 2 ml deionized water.

Esclusione di responsabilità

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

Eyeshields, Gloves, type N95 (US)


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E Yee et al.
Journal of immunological methods, 225(1-2), 125-130 (1999-06-12)
Three ELISA methods for the quantitation of haptoglobin (Hp) in plasma and albumin are described: a polystyrene direct adsorption method and capture methods with antibody and hemoglobin. Hp aggregates generated by 60 degrees C heating showed as much as a
Identification of haptoglobin switch-on status in archived placental specimens indicates antenatal exposure to inflammation and potential participation of the fetus in triggering preterm birth
McCarthy M, et al.
Placenta, 62(2), 50-57 (2018)
Vivekananda Shetty et al.
Clinical proteomics, 9(1), 10-10 (2012-08-04)
In approximately 80% of patients, ovarian cancer is diagnosed when the patient is already in the advanced stages of the disease. CA125 is currently used as the marker for ovarian cancer; however, it lacks specificity and sensitivity for detecting early
Haptoglobin 2 allele associates with unstable carotid plaque and major cardiovascular events
Ijas P, et al.
Atherosclerosis, 230(2), 228-234 (2013)
Diminished acute phase response and increased hepatic inflammation of aged rats in response to intraperitoneal injection of lipopolysaccharide
Gomez C, et al.
The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences, 63(12), 1299-1306 (2008)

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