H6166
Interferon α 2B human
HumanKine®, ≥95% (SDS-PAGE), recombinant, expressed in HEK 293 cells, lyophilized powder, suitable for cell culture
Sinonimo/i:
IFN α 2B, IFN Alfa 2b, INF α 2B, INF Alfa 2b, Interferon Alfa 2b
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About This Item
Prodotti consigliati
Nome del prodotto
Interferon α 2B human, IFN-α 2B, recombinant, expressed in HEK 293 cells, HumanKine®, suitable for cell culture
Origine biologica
human
Livello qualitativo
Ricombinante
expressed in HEK 293 cells
Saggio
≥95% (SDS-PAGE)
Stato
lyophilized powder
Potenza
≤0.12 ng/mL EC50
Qualità
endotoxin tested
PM
dimer 16 kDa (glycosylated)
Confezionamento
poly bottle of 10 μg (in poly bottle)
Produttore/marchio commerciale
HumanZyme
tecniche
cell culture | mammalian: suitable
Impurezze
≤1EU/mg
N° accesso UniProt
Temperatura di conservazione
−20°C
Informazioni sul gene
human ... IFNA2(3440)
Descrizione generale
The interferon α 2 (IFN-α2) exists in three forms 2a, 2b and 2c. It consists of 165 amino acids and five α helices. IFN-α2B is found structurally stable at pH 7. The recombinant IFN-α is nonglycosylated compared to the natural human IFN-α.
Azioni biochim/fisiol
Interferon α 2B (IFN-α 2B) belongs to the type I interferon protein family. It is produced by many cell types in response to viral infection. IFN-α 2B has antiproliferative and antitumor activities, as well as induction of apoptosis and the inflammatory response. It enhances the expression of MHC proteins by increasing the presentation of antigen peptides and activates cytotoxic T-cells.
Stato fisico
Lyophilized from a 0.2 μm filtered solution of 1x PBS.
Nota sulla preparazione
HumanKine IFN-α 2B is a glycosylated monomer expressed in HEK 293 cells with an apparent molecular mass of 16 kDa. Production in human 293 cells offers authentic glycosylation. Glycosylation contributes to stability in cell growth media and other applications.
Risultati analitici
The specific activity was determined by the dose-dependent proliferation of WISH (heteroploid human amnion cell line) in presence of VSV ( vesicular stomatitis virus).
Note legali
HumanKine is a registered trademark of Proteintech Group, Inc. and Humanzyme, Inc
Codice della classe di stoccaggio
11 - Combustible Solids
Classe di pericolosità dell'acqua (WGK)
WGK 3
Punto d’infiammabilità (°F)
Not applicable
Punto d’infiammabilità (°C)
Not applicable
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