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Key Documents

Altri documenti

H3661

Sigma-Aldrich

4′-Hydroxydiclofenac

≥98% (HPLC)

Sinonimo/i:

4′-Hydroxy Diclofenac

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About This Item

Formula empirica (notazione di Hill):
C14H11Cl2NO3
Numero CAS:
64118-84-9
Peso molecolare:
312.15
Beilstein:
4198042
Numero MDL:
MFCD01671980
Codice UNSPSC:
12161501
ID PubChem:
24895589
NACRES:
NA.47

Livello qualitativo

200

Saggio

≥98% (HPLC)

Confezionamento

vial of 5 mg

Temperatura di conservazione

−20°C

Stringa SMILE

OC(=O)Cc1ccccc1Nc2c(Cl)cc(O)cc2Cl

InChI

1S/C14H11Cl2NO3/c15-10-6-9(18)7-11(16)14(10)17-12-4-2-1-3-8(12)5-13(19)20/h1-4,6-7,17-18H,5H2,(H,19,20)
KGVXVPRLBMWZLG-UHFFFAOYSA-N

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Descrizione generale

4′-Hydroxydiclofenac is an important metabolite of aceclofenac, seen mainly in rats. It is the important oxidative metabolite found in urine.
CYP2C9 metabolite of diclofenac.

Applicazioni

4′-Hydroxydiclofenac has been used to investigate the effect of gentiopicroside (GE) on human cytochrome P450 enzymes in vitro. It has also been used as an enzyme marker to study its metabolic activities in different in vitro liver models.

Avvertenze

Danger

Indicazioni di pericolo

H301,H315,H318,H335,H410

Classi di pericolo

Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Dam. 1 - Skin Irrit. 2 - STOT SE 3

Organi bersaglio

Respiratory system

Codice della classe di stoccaggio

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

Classe di pericolosità dell'acqua (WGK)

WGK 3

Dispositivi di protezione individuale

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges

Certificati d'analisi (COA)

Cerca il Certificati d'analisi (COA) digitando il numero di lotto/batch corrispondente. I numeri di lotto o di batch sono stampati sull'etichetta dei prodotti dopo la parola ‘Lotto’ o ‘Batch’.

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