GE17-5481-51

HiTrap^® Capto^™ Core 700

Cytiva 17-5481-51, pack of 5 × 1 mL

• Sinonimo/i: Capto Core 700 Column
• Codice UNSPSC: 23151817
• NACRES: NA.56

Proprietà

• ligand: octylamine
• Confezionamento: pack of 5 × 1 mL
• Produttore/marchio commerciale: Cytiva 17-5481-51
• Parametri: 5 bar
• Diam. int. colonna: 7 mm
• Matrice: highly cross-linked agarose
• Dimens. media delle particelle: 75 (d₅₀v is the median particle size of the cumulative volume distribution)
• cleaning: 3-14(pH interval where the medium can be subjected to, for cleaning- or sanitization-in-place.)
• Intervallo di esercizio: 2-14(pH interval where the medium can be operated without significant change in function.)
• Capacità: ~13 mg binding capacity (ovalbumin)
• Compatibilità: suitable for bioprocess medium

Descrizione

Descrizione generale

Dynamic binding capacities were measured at 10% breakthrough with a residence time of 3 min (1.6 ml/min = 200 cm/h) in HiScreen columns. Buffer: 20 mM Tris-HCl, 150 mM NaCl, pH 7.5.

HiTrap Capto Core 700 is prepacked with Capto Core 700, a multimodal BioProcess resin for intermediate purification and polishing of viruses and other large biomolecules. Capto Core 700 is a novel, layered bead chromatography resin consisting of a porous outer layer and ligand-activated core. The octylamine ligands found in the core of the beads are multimodal, being both hydrophobic and positively charged. These internalized ligands bind impurities strongly over a wide range of pH and salt concentration. The pores of the bead outer layer prevent large targets (Mr > 700 000) from binding to the ligands while smaller impurities can enter freely into the beads where they are captured.

Caratteristiche e vantaggi

• High capacity and productivity in flowthrough mode.
• Prepacked HiTrap columns for easy screening and convenient process development, as well as small scale purification.
• Wide operational window of pH and conductivity.

Stoccaggio e stabilità

Please be aware this product may be shipped 90 days before the expiration date. For more information on the batch specific expiration date, please contact technical service.

Store at 4 to 30 °C (20% Ethanol)

Risultati analitici

To view the Certificate of Analysis for this product, please visit www.cytiva.com.

Note legali

Capto is a trademark of Cytiva

HiTrap is a registered trademark of Cytiva

Informazioni sulla sicurezza

• Pittogrammi: GHS02
• Avvertenze: Warning
• Indicazioni di pericolo: H226
• Consigli di prudenza: P280 - P210 - P241 - P235 - P303 + P361 + P353 - P501
• Codice della classe di stoccaggio: 3 - Flammable liquids