D9442

Anti-Dopamine Transporter, Extracellular Loop 2 antibody produced in rabbit

affinity isolated antibody, buffered aqueous glycerol solution

• Sinonimo/i: Anti-DAT
• Numero MDL: MFCD02262815
• Codice UNSPSC: 12352203
• NACRES: NA.41

Proprietà

• Origine biologica: rabbit
• Livello qualitativo: 200
• Coniugato: unconjugated
• Forma dell’anticorpo: affinity isolated antibody
• Tipo di anticorpo: primary antibodies
• Clone: polyclonal
• Forma fisica: buffered aqueous glycerol solution
• Reattività contro le specie: monkey, human
• tecniche: immunohistochemistry: 1:1,000 using formaldehyde-fixed human and monkey brain sections; western blot: 1:1,000 using SDS-solubilized human striatal samples
• N° accesso UniProt: Q01959
• Condizioni di spedizione: wet ice
• Temperatura di conservazione: −20°C
• modifica post-traduzionali bersaglio: unmodified
• Informazioni sul gene: human ... SLC6A3(6531)

Descrizione

Immunogeno

synthetic peptide from the extracellular loop 2 region of human dopamine transporter.

Applicazioni

Anti-Dopamine Transporter, Extracellular Loop 2 antibody produced in rabbit is suitable at a working dilution of 1:1000 for western blotting using SDS-solubilized human striatal samples and for immunohistochemistry using formaldehyde-fixed human and monkey brain sections.

Azioni biochim/fisiol

The dopamine transporter (DAT1) acts to take released dopamine back up into presynaptic terminals and has been implicated in human disorders such as parkinsonism, Tourette syndrome, and substance abuse. DAT1 gene is a primary target gene for ADHD (Attention deficit hyperactivity disorder). DAT polymorphism along with maternal prenatal smoking is associated with childhood hyperactivity-impulsivity and inattentiveness.

Descrizione del bersaglio

The dopamine transporter (DAT1) acts to take released dopamine back up into presynaptic terminals and has been implicated in human disorders such as parkinsonism, Tourette syndrome, and substance abuse.

Stato fisico

Solution in 10 mM HEPES, pH 7.5, 150 mM NaCl, 100 μg/mL BSA, and 50% glycerol.

Esclusione di responsabilità

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 10 - Combustible liquids
• Classe di pericolosità dell'acqua (WGK): WGK 3
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable