C9523

Sodium cholesteryl sulfate

• Sinonimo/i: 5-Cholesten-3β-ol sulfate sodium salt, Cholesterol 3-sulfate sodium salt, Cholesteryl sodium sulfate, Cholesteryl sulfate sodium salt
• Formula empirica (notazione di Hill): C₂₇H₄₅NaO₄S
• Numero CAS: 2864-50-8
• Peso molecolare: 488.70
• Beilstein: 3899884
• Numero MDL: MFCD00079091
• Codice UNSPSC: 41141804
• eCl@ss: 39023139
• ID PubChem: 24893166
• NACRES: NA.77

Proprietà

• Origine biologica: synthetic
• Livello qualitativo: 200
• Descrizione: anionic
• Saggio: ≥98% (TLC)
• Stato: powder
• Condizioni di spedizione: ambient
• Temperatura di conservazione: −20°C
• Stringa SMILE: [H][C@@]([C@H](C)CCCC(C)C)([C@@]1(C)CC[C@@]23[H])CC[C@]1([C@](CC=C4C[C@H](CC[C@]34C)OS([O-])(=O)=O)2[H])[H].[Na+]
• InChI: 1S/C27H46O4S.Na/c1-18(2)7-6-8-19(3)23-11-12-24-22-10-9-20-17-21(31-32(28,29)30)13-15-26(20,4)25(22)14-16-27(23,24)5;/h9,18-19,21-25H,6-8,10-17H2,1-5H3,(H,28,29,30);/q;+1/p-1/t19-,21+,22+,23-,24+,25+,26+,27-;/m1./s1; LMPVQXVJTZWENW-KPNWGBFJSA-M

Descrizione

Applicazioni

Sodium cholesteryl sulfate was used as the source of cholesterol in the preparation of Edgar′s growth medium used for embryology experiments. It was used as a standard for the separation of human stratum corneum lipids by thin layer chromatography.

Azioni biochim/fisiol

Cholesteryl sulfate is a natural constituent of human spermatozoa and has major role in the maturation of sperms. It could also be involved in the capacitation of sperms and enables ovum penetration. Low concentrations of cholesteryl sulfate inhibits acrosin, the proteinase present in sperm acrosome that facilitates ovum penetration.

Nota sulla preparazione

Sodium cholesteryl sulfate yields clear, colorless solution in chloroform-methanol (1:1) mixture at 10 mg/ml.

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 11 - Combustible Solids
• Classe di pericolosità dell'acqua (WGK): WGK 3
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable
• Dispositivi di protezione individuale: Eyeshields, Gloves, type N95 (US)