C4982
Cytochrome P450 human
3A4 isozyme microsomes, with P450 reductase and cytochrome b5, recombinant, expressed in baculovirus infected insect cells (BTI-TN-5B1-4)
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About This Item
Numero MDL:
Codice UNSPSC:
12161501
NACRES:
NA.47
Prodotti consigliati
Origine biologica
human
Livello qualitativo
Ricombinante
expressed in baculovirus infected insect cells (BTI-TN-5B1-4)
Forma fisica
solution
PM
45-60 kDa
Confezionamento
vial of ~0.5 nmol
vial of ≥25 units
N° accesso UniProt
applicazioni
cell analysis
Condizioni di spedizione
dry ice
Temperatura di conservazione
−70°C
Informazioni sul gene
human ... CYP3A4(1576)
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Azioni biochim/fisiol
Cytochrome P450 is a heterogeneous family of isozymes whose primary function is to oxidize small molecules, both as a function of intermediary metabolism (e.g., fatty acids) and to detoxify exogenous compounds (drugs or toxins). Some isoforms have narrow substrate specificity, while others are promiscuous.
Altre note
Microsomes containing recombinant human CYP3A4 and recombinant rabbit NADPH-P450 reductase
Definizione di unità
One unit will convert 1 nanomole of testosterone to 6β-hydroxytestosterone per minute at pH 7.4 at 37 °C.
Stato fisico
Solution in 100 mM potassium phosphate buffer, pH 7.4.
Codice della classe di stoccaggio
10 - Combustible liquids
Classe di pericolosità dell'acqua (WGK)
WGK 2
Punto d’infiammabilità (°F)
Not applicable
Punto d’infiammabilità (°C)
Not applicable
Certificati d'analisi (COA)
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