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C3630

Sigma-Aldrich

Creatine monohydrate

≥98%, suitable for cell culture

Sinonimo/i:

Creatine hydrate, Creatine, monohydrate, N-(aminoiminomethyl)-N-methyl-glycine hydrate

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About This Item

Formula empirica (notazione di Hill):
C4H9N3O2 · H2O
Numero CAS:
6020-87-7
Peso molecolare:
149.15
Beilstein:
7942755
Numero CE:
200-306-6
Numero MDL:
MFCD00071582
Codice UNSPSC:
12352209
ID PubChem:
24892629
NACRES:
NA.26

product name

Creatine monohydrate, ≥98%

Livello qualitativo

200

Saggio

≥98%

Forma fisica

powder

tecniche

cell culture | mammalian: suitable

Colore

white to off-white

Punto di fusione

292 °C

Stringa SMILE

O.CN(CC(O)=O)C(N)=N

InChI

1S/C4H9N3O2.H2O/c1-7(4(5)6)2-3(8)9;/h2H2,1H3,(H3,5,6)(H,8,9);1H2
MEJYXFHCRXAUIL-UHFFFAOYSA-N

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Applicazioni

Creatine (Cr) and phosphocreatine (PCr) are involved with rapid ATP production primarily in skeletal muscle tissue via the action of creatine kinase(s). Creatine may be used as a supplement to study its uptake mechanism and metabolism of action.

Azioni biochim/fisiol

Creatine is a nitrogenous compound that acts as a high-energy reservoir for the rapid regeneration of ATP. Approximately 95% of creatine is found in skeletal muscle, primarily as phosphocreatine. Creatine can be acquired through dietary consumption or formed from L-arginine, glycine, and L-methionine in a multi-step reaction that occurs in the kidneys and liver. Creatine is then transported to muscle tissue. Creatine supplementation is used for the enhancement of sports performance, primarily by increasing muscle mass. Creatine is also being investigated as a treatment of neuromuscular diseases, where it may aid in neuroprotection and by improving the cellular bioenergetic state.

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

dust mask type N95 (US), Eyeshields, Gloves

Certificati d'analisi (COA)

Cerca il Certificati d'analisi (COA) digitando il numero di lotto/batch corrispondente. I numeri di lotto o di batch sono stampati sull'etichetta dei prodotti dopo la parola ‘Lotto’ o ‘Batch’.

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3-Guanidinopropionic acid

Sigma-Aldrich

G6878

3-Guanidinopropionic acid

Taurina suitable for cell culture, meets USP testing specifications

Sigma-Aldrich

T8691

Taurina

Phosphocreatine disodium salt hydrate ≥97%

Sigma-Aldrich

P7936

Phosphocreatine disodium salt hydrate

Creatinine-(methyl-d3) 98 atom % D

Sigma-Aldrich

485446

Creatinine-(methyl-d3)

Jeffrey S Martin et al.
Journal of the International Society of Sports Nutrition, 14, 38-38 (2017-09-30)
We sought to determine if a pre-workout supplement (PWS), containing multiple ingredients thought to enhance blood flow, increases hyperemia associated with resistance training compared to placebo (PBO). Given the potential interaction with training loads/time-under-tension, we evaluated the hyperemic response at
Andrina Stäubli et al.
Human molecular genetics, 26(21), 4203-4214 (2017-11-01)
Membrane transporters influence biological functions in the ocular lens. Here, we investigate the monocarboxylate transporter 12 (MCT12), also called creatine transporter 2 (CRT2), which is found in the ocular lens and is involved in cataract. As the age-related form affects
Caro-Lyne DesRoches et al.
Gene, 565(2), 187-191 (2015-04-12)
Creatine transporter deficiency (CRTR-D) is an X-linked inherited disorder of creatine transport. All males and about 50% of females have intellectual disability or cognitive dysfunction. Creatine deficiency on brain proton magnetic resonance spectroscopy and elevated urinary creatine to creatinine ratio
Clare E Turner et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 35(4), 1773-1780 (2015-01-30)
Impairment or interruption of oxygen supply compromises brain function and plays a role in neurological and neurodegenerative conditions. Creatine is a naturally occurring compound involved in the buffering, transport, and regulation of cellular energy, with the potential to replenish cellular
Domenic A LaRosa et al.
Pediatric research, 80(6), 852-860 (2016-07-29)
Maternal antenatal creatine supplementation protects the brain, kidney, and diaphragm against the effects of birth asphyxia in the spiny mouse. In this study, we examined creatine's potential to prevent damage to axial skeletal muscles. Pregnant spiny mice were fed a
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