C1112

CP-55940

>98% (HPLC), powder

• Sinonimo/i: 5-(1,1-Dimethylheptyl)-2-[5-hydroxy-2-(3-hydroxypropyl)cyclohexyl]phenol
• Formula empirica (notazione di Hill): C₂₄H₄₀O₃
• Numero CAS: 83002-04-4
• Peso molecolare: 376.57
• Numero MDL: MFCD00673965
• Codice UNSPSC: 12352200
• ID PubChem: 24278295
• NACRES: NA.77

Proprietà

• Livello qualitativo: 100
• Saggio: >98% (HPLC)
• Forma fisica: powder
• Attività ottica: [α]/D -24 to -30°, c = 0.2 in chloroform-d
• Controllo stupefacenti: regulated under CDSA - not available from Sigma-Aldrich Canada
• Condizioni di stoccaggio: desiccated
• Solubilità: DMSO: 15 mg/mL; H₂O: slightly soluble
• Temperatura di conservazione: 2-8°C
• Stringa SMILE: CCCCCCC(C)(C)c1ccc([C@@H]2C[C@H](O)CC[C@H]2CCCO)c(O)c1
• InChI: 1S/C24H40O3/c1-4-5-6-7-14-24(2,3)19-11-13-21(23(27)16-19)22-17-20(26)12-10-18(22)9-8-15-25/h11,13,16,18,20,22,25-27H,4-10,12,14-15,17H2,1-3H3/t18-,20-,22-/m1/s1; YNZFFALZMRAPHQ-SYYKKAFVSA-N
• Informazioni sul gene: human ... CNR1(1268) , CNR2(1269) ; rat ... Cnr1(25248)

Descrizione

Applicazioni

CP-55940 has been used as a cannabinoid agonists in Chinese hamster ovary (CHO) expressing cannabinoid receptor 2(CB2).

Azioni biochim/fisiol

CP-55940 is a nonclassical cannabinoids (NCCs), which lack the tetrahydropyran ring. CP-55940, a derivative of CP-47,497 is enantioselective. Due to its amphipathic nature, CP-55940 tethers in biological membrane making it favourable for the cannabinoid receptor interaction. CP-55940 belongs to the cyclohexylphenol category and modulates the brain lipidome leading to dysregulation especially during adolescence. It inhibits capsaicin-evoked sensitization of nociceptive and spinal dorsal horn neurons.

CP-55940 is a selective cannabinoid receptor agonist.

Caratteristiche e vantaggi

This compound is featured on the Cannabinoid Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Informazioni sulla sicurezza

• Pittogrammi: GHS07
• Avvertenze: Warning
• Indicazioni di pericolo: H336
• Consigli di prudenza: P261 - P271 - P304 + P340 + P312 - P403 + P233 - P405 - P501
• Classi di pericolo: STOT SE 3
• Organi bersaglio: Respiratory system
• Codice della classe di stoccaggio: 11 - Combustible Solids
• Classe di pericolosità dell'acqua (WGK): WGK 3
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable
• Dispositivi di protezione individuale: Eyeshields, Gloves, type N95 (US)