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Key Documents

C0742

Sigma-Aldrich

CKI-7 dihydrochloride

≥98% (HPLC), solid, CK1 inhibitor

Sinonimo/i:

N-(2-Aminoethyl)-5-chloroisoquinoline-8-sulphonamide dihydrochloride

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About This Item

Formula empirica (notazione di Hill):
C11H12ClN3O2S · 2HCl
Numero CAS:
Peso molecolare:
358.67
Numero MDL:
Codice UNSPSC:
12352200
ID PubChem:
NACRES:
NA.77

product name

CKI-7 dihydrochloride, ≥98% (HPLC), solid

Saggio

≥98% (HPLC)

Forma fisica

solid

Condizioni di stoccaggio

desiccated

Colore

white to light tan

Solubilità

H2O: >5 mg/mL

Temperatura di conservazione

−20°C

Stringa SMILE

Cl[H].Cl[H].NCCNS(=O)(=O)c1ccc(Cl)c2ccncc12

InChI

1S/C11H12ClN3O2S.2ClH/c12-10-1-2-11(18(16,17)15-6-4-13)9-7-14-5-3-8(9)10;;/h1-3,5,7,15H,4,6,13H2;2*1H
JUAVTXYOCISSSL-UHFFFAOYSA-N

Azioni biochim/fisiol

CKI-7 is a CK1 inhibitor; also inhibits SGK, S6K1 and MSK1. CKI-7 inhibits SGK as potently as CK1. IC50 = 6 μM.

Avvertenza

Material is hygroscopic

Pittogrammi

Skull and crossbones

Avvertenze

Danger

Indicazioni di pericolo

Classi di pericolo

Acute Tox. 3 Oral

Codice della classe di stoccaggio

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges


Certificati d'analisi (COA)

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Sigma-Aldrich

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