B8686

(+)-N-3-Benzyl Nirvanol

≥98% (HPLC), powder, CYP2C19 inhibitor

• Sinonimo/i: 5-ethyl-5-phenyl-3-(phenylmethyl)-2,4-imidazolidinedione, 5-ethyl-5-phenyl-3-(phenylmethyl)-hydantoin
• Formula empirica (notazione di Hill): C₁₈H₁₈N₂O₂
• Numero CAS: 790676-40-3
• Peso molecolare: 294.35
• Numero MDL: MFCD09840024
• Codice UNSPSC: 12161501
• ID PubChem: 329773138
• NACRES: NA.77

Proprietà

• Nome del prodotto: (+)-N-3-Benzyl Nirvanol, ≥98% (HPLC), powder
• Livello qualitativo: 100
• Saggio: ≥98% (HPLC)
• Stato: powder
• Solubilità: DMSO: >20 mg/mL; H₂O: insoluble
• Temperatura di conservazione: 2-8°C
• Stringa SMILE: CC[C@]1(NC(=O)N(Cc2ccccc2)C1=O)c3ccccc3
• InChI: 1S/C18H18N2O2/c1-2-18(15-11-7-4-8-12-15)16(21)20(17(22)19-18)13-14-9-5-3-6-10-14/h3-12H,2,13H2,1H3,(H,19,22)/t18-/m0/s1; ZMZDHUHMXXALFX-SFHVURJKSA-N

Descrizione

Applicazioni

(+)-N-3-Benzylnirvanol may be used as a cytochrome P450 2C19 (CYP2C19) inhibitor in a comparison study to treat cocktail and individual substrates for the screening for potent cytochrome P450 (CYP) inhibition. It may also be used in comparative studies to investigate its potential as CYP and non-CYP selective inhibitors of CYP2C19 in suspended human hepatocytes.

Azioni biochim/fisiol

(+)-N-3-Benzyl-nirvanol is a potent selective CYP2C19 inhibitor.

(+)-N-3-Benzyl-nirvanol is a potent selective CYP2C19 inhibitor. CYP2C19 has a high frequency of drug resistance; highly polymorphic.

(+)-N-3-Benzylnirvanol serves as an inhibitor of cytochrome P450 2B6 (CYP2B6).

Informazioni sulla sicurezza

• Pittogrammi: GHS07,GHS09
• Avvertenze: Warning
• Indicazioni di pericolo: H302,H319,H400
• Consigli di prudenza: P264 - P270 - P273 - P280 - P301 + P312 - P305 + P351 + P338
• Classi di pericolo: Acute Tox. 4 Oral - Aquatic Acute 1 - Eye Irrit. 2
• Codice della classe di stoccaggio: 11 - Combustible Solids
• Classe di pericolosità dell'acqua (WGK): WGK 3
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable
• Dispositivi di protezione individuale: dust mask type N95 (US), Eyeshields, Gloves