B7283

Benserazide hydrochloride

≥98% (HPLC), solid, L-aromatic amino acid decarboxylase inhibitor

• Sinonimo/i: DL-Serine 2-(2,3,4-trihydroxybenzyl)hydrazide hydrochloride
• Formula empirica (notazione di Hill): C₁₀H₁₅N₃O₅ · HCl
• Numero CAS: 14919-77-8
• Peso molecolare: 293.70
• Numero CE: 238-991-9
• Numero MDL: MFCD00078571
• Codice UNSPSC: 12352125
• ID PubChem: 24277886
• NACRES: NA.77

Proprietà

• product name: Benserazide hydrochloride, ≥98% (HPLC), solid
• Origine biologica: synthetic
• Saggio: ≥98% (HPLC)
• Forma fisica: solid
• Solubilità: H₂O: 10 mg/mL
• Ideatore: Roche
• Temperatura di conservazione: room temp
• Stringa SMILE: Cl.NC(CO)C(=O)NNCc1ccc(O)c(O)c1O
• InChI: 1S/C10H15N3O5.ClH/c11-6(4-14)10(18)13-12-3-5-1-2-7(15)9(17)8(5)16;/h1-2,6,12,14-17H,3-4,11H2,(H,13,18);1H; ULFCBIUXQQYDEI-UHFFFAOYSA-N
• Informazioni sul gene: human ... DDC(1644)

Descrizione

Descrizione generale

Benserazide is a peripheral decarboxylase inhibitor.

Applicazioni

Benserazide has been used:

• to inhibit dopa-decarboxylase
• to induce dyskinesia
• to test on purified bacterial TDCs to assess the extent to which it could affect bacterial decarboxylases
• as a peripheral dopa decarboxylase inhibitor to treat mice

Azioni biochim/fisiol

Benserazide can block HK2 enzymatic activity in vitro. It is used along with levodopa to treat Parkinson′s disease.

Inhibitor of L-aromatic amino acid decarboxylase.

Caratteristiche e vantaggi

This compound is a featured product for Neuroscience research. Click here to discover more featured Neuroscience products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

This compound was developed by Roche. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Altre note

2024 CiteAb Award Winner for Supplier Succeeding in Parkinson′s Research

Informazioni sulla sicurezza

• Pittogrammi: GHS07
• Avvertenze: Warning
• Indicazioni di pericolo: H315,H319,H335
• Consigli di prudenza: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Classi di pericolo: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Organi bersaglio: Respiratory system
• Codice della classe di stoccaggio: 11 - Combustible Solids
• Classe di pericolosità dell'acqua (WGK): WGK 2
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable
• Dispositivi di protezione individuale: dust mask type N95 (US), Eyeshields, Gloves