Passa al contenuto
Merck
Tutte le immagini(7)

Documenti fondamentali

A8763

Sigma-Aldrich

Albumina

lyophilized powder, essentially globulin free, ≥99% (agarose gel electrophoresis)

Sinonimo/i:

HSA

Autenticatiper visualizzare i prezzi riservati alla tua organizzazione & contrattuali


About This Item

Numero CAS:
Numero CE:
Numero MDL:
Codice UNSPSC:
12352202
eCl@ss:
42010201
NACRES:
NA.25

Origine biologica

human

Livello qualitativo

Saggio

≥99% (agarose gel electrophoresis)

Forma fisica

lyophilized powder

PM

monomer calculated mol wt 66478 Da

tecniche

ELISA: suitable
tissue culture: suitable
western blot: suitable

Impurezze

HIV I and HIVII, HCV and HBsAg, tested negative

Solubilità

H2O: soluble 20 mg/mL

N° accesso UniProt

Temperatura di conservazione

2-8°C

InChI

1S/C3F8/c4-1(5,2(6,7)8)3(9,10)11
QYSGYZVSCZSLHT-UHFFFAOYSA-N

Informazioni sul gene

human ... ALB(213)

Cerchi prodotti simili? Visita Guida al confronto tra prodotti

Descrizione generale

Albumin is the most copious protein in blood plasma. Liver produces human albumin.

Applicazioni

Albumin was used to test its effect on the in vitro bactericidal activity of cefditoren against penicillin-resistant Streptococcus pneumonia. It has been clinically used in serious and often life-threatening conditions, such as shock and blood loss due to trauma, burns, and surgery.
Albumin was used to study albumin-induced apoptosis in proximal tubule cells. It was also used in cell adhesion molecules and surface treatment studies.

Azioni biochim/fisiol

L′albumina sierica svolge le funzioni di proteina carrier per gli steroidi, gli acidi grassi e gli ormoni tiroidei ed è di vitale importanza nella regolazione delle pressioni colloido-osmotiche del sangue. È stato anche osservato che l′albumina si lega a sostanze esogene, farmaci in particolare (per es. ibuprofene, warfarin) influenzandone pesantemente la farmacocinetica. Lo stress ossidativo che determina modificazioni dello stato redox dell′albumina ha effetti molto variabili sulla sua funzione fisiologica.
Serum albumin functions as a carrier protein for steroids, fatty acids, and thyroid hormones, and is vital in regulating the colloidal osmotic pressures of blood. Albumin can also bind to exogenous substances, particularly drugs (e.g., ibuprofen, warfarin), and strongly influences their pharmacokinetics. Oxidative stress leading to changes in the redox state of albumin has varied effects on its physiological function.

Altre note

Vedere maggiori informazioni sull′albumina sierica umana.

Esclusione di responsabilità

RESEARCH USE ONLY. This product is regulated in France when intended to be used for scientific purposes, including for import and export activities (Article L 1211-1 paragraph 2 of the Public Health Code). The purchaser (i.e. enduser) is required to obtain an import authorization from the France Ministry of Research referred in the Article L1245-5-1 II. of Public Health Code. By ordering this product, you are confirming that you have obtained the proper import authorization.

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

Eyeshields, Gloves


Certificati d'analisi (COA)

Cerca il Certificati d'analisi (COA) digitando il numero di lotto/batch corrispondente. I numeri di lotto o di batch sono stampati sull'etichetta dei prodotti dopo la parola ‘Lotto’ o ‘Batch’.

Possiedi già questo prodotto?

I documenti relativi ai prodotti acquistati recentemente sono disponibili nell’Archivio dei documenti.

Visita l’Archivio dei documenti

Tamás Pivarcsik et al.
Pharmaceuticals (Basel, Switzerland), 14(6) (2021-06-03)
In this work, the various biological activities of eight organoruthenium(II) complexes were evaluated to reveal correlations with their stability and reactivity in aqueous media. Complexes with general formula [Ru(η6-p-cymene)(X,Y)(Z)] were prepared, where (X,Y) represents either an O,O-ligand (β-diketone), N,O-ligand (8-hydroxyquinoline)
H K Parmentier et al.
Poultry science, 88(3), 536-542 (2009-02-13)
To mimic airborne immune challenges, layer hens were intratracheally and concurrently challenged with various doses of the protein antigen human serum albumin (HuSA) and the pathogen-associated molecular pattern lipopolysaccharide (LPS) at 7 and 13 wk of age. All groups received
Orsolya Dömötör et al.
Journal of pharmaceutical and biomedical analysis, 154, 321-331 (2018-03-24)
Binding interactions between human serum albumin (HSA) and four approved epidermal growth factor receptor (EGFR) inhibitors gefitinib (GEF), erlotinib (ERL), afatinib (AFA), osimertinib (OSI), as well as the experimental drug KP2187, were investigated by means of spectrofluorometric and molecular modelling
Kevin R Trabbic et al.
Scientific reports, 9(1), 5662-5662 (2019-04-07)
We have previously studied the generation of immune responses after vaccination with tumor-associated carbohydrate antigen (TACA)-containing glycopeptides from the tandem repeat (TR) sequence of MUC4, an aberrantly expressed mucin in pancreatic adenocarcinomas. A specific lead antigen from that study containing
Nitin Agrawal et al.
Lab on a chip, 8(12), 2054-2061 (2008-11-22)
Neutrophil directional migration in response to chemical gradients, also known as chemotaxis, is one of the key phenomena in the immune responses against bacterial infection. To better study neutrophils chemotaxis, several in vitro assays have been developed that replicate chemotactic

Il team dei nostri ricercatori vanta grande esperienza in tutte le aree della ricerca quali Life Science, scienza dei materiali, sintesi chimica, cromatografia, discipline analitiche, ecc..

Contatta l'Assistenza Tecnica.