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A7631

Sigma-Aldrich

(+)- L-ascorbato di sodio

crystalline, ≥98%

Sinonimo/i:

Acido L(+)-ascorbico, Vitamina C

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About This Item

Formula empirica (notazione di Hill):
C6H7NaO6
Numero CAS:
Peso molecolare:
198.11
Beilstein:
3767246
Numero CE:
Numero MDL:
Codice UNSPSC:
12352205
eCl@ss:
34058010
ID PubChem:
NACRES:
NA.79

Origine biologica

synthetic

Saggio

≥98%

Forma fisica

crystalline

tecniche

HPLC: suitable

Colore

white to off-white

Punto di fusione

220 °C (dec.) (lit.)

Stringa SMILE

[Na+].OC[C@H](O)[C@H]1OC(=O)C(O)=C1[O-]

InChI

1S/C6H8O6.Na/c7-1-2(8)5-3(9)4(10)6(11)12-5;/h2,5,7-10H,1H2;/q;+1/p-1/t2-,5+;/m0./s1
PPASLZSBLFJQEF-RXSVEWSESA-M

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Descrizione generale

Ascorbic acid, also known as vitamin C, is a water-soluble vitamin. L-Ascorbic acid is a reducing agent.

Applicazioni

(+)-Sodium L-ascorbate has been used:
  • as a component of cutting solution for storing brain slices of rats
  • as a component of patch pipette internal solution for imaging Ca2+ transients evoked by action potential in rat brain slices
  • as a supplement for arterial smooth muscle cell (SMC) cultures to encourage collagen production

Azioni biochim/fisiol

Ascorbic acid exhibits anti-oxidant properties. It is a primary substrate for detoxifying hydrogen peroxide. Ascorbic acid is a co-factor for the synthesis of adrenal steroids and catecholamines. L-Ascorbic acid (Vitamin C) is a water soluble molecule used in a wide variety of applications, including cell culture, as a reducing agent that helps reduce oxidative stress. L-Ascorbate can be regenerated by biological systems.

Avvertenza

May darken in storage.

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 1

Dispositivi di protezione individuale

Eyeshields, Gloves, type N95 (US)


Certificati d'analisi (COA)

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Vitamin C is an important cofactor for both adrenal cortex and adrenal medulla
Patak P, et al.
Endocrine Research, 30(4), 871-875 (2004)
Imaging calcium concentration dynamics in small neuronal compartments
Yasuda R, et al.
Science's STKE : Signal Transduction Knowledge Environment, 219, pl5-pl5 (2004)
Exogenous ascorbic acid (vitamin C) increases resistance to salt stress and reduces lipid peroxidation
Shalata A and Neumann P M
Journal of Experimental Botany, 52(364), 2207-2211 (2001)
Differential roles of endothelin-1 in angiotensin II-induced atherosclerosis and aortic aneurysms in apolipoprotein E-null mice
Suen RS, et al.
The American Journal of Pathology, 179(3), 1549-1559 (2011)
Jiali Zhang et al.
Chemical communications (Cambridge, England), 46(7), 1112-1114 (2010-02-04)
We demonstrated that the individual graphene oxide sheets can be readily reduced under a mild condition using L-ascorbic acid (L-AA). This simple approach should find practical applications in large scale production of water soluble graphene.

Articoli

Antioxidants protect biological systems from oxidative damage produced by oxygen-containing free radicals and from redoxactive transition metal ions such as iron, copper, and cadmium.

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