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Key Documents

A6608

Sigma-Aldrich

Albumina

recombinant, expressed in Saccharomyces cerevisiae, aqueous solution, 10% in aqueous buffer, ≥99% (agarose gel electrophoresis)

Sinonimo/i:

rHSA

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About This Item

Formula empirica (notazione di Hill):
C2936H4624N786O889S41
Numero CAS:
Peso molecolare:
66471.53
Numero MDL:
Codice UNSPSC:
12352202
eCl@ss:
42010201
NACRES:
NA.25

Origine biologica

human

Livello qualitativo

Ricombinante

expressed in Saccharomyces cerevisiae

Saggio

≥99% (agarose gel electrophoresis)

Forma fisica

aqueous solution

PM

monomer ~67 kDa

Concentrazione

10% in aqueous buffer

tecniche

cell culture | mammalian: suitable

N° accesso UniProt

Temperatura di conservazione

2-8°C

InChI

1S/C3F8/c4-1(5,2(6,7)8)3(9,10)11
QYSGYZVSCZSLHT-UHFFFAOYSA-N

Informazioni sul gene

human ... ALB(213)

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Descrizione generale

Albumin constitutes 25% of the proteins produced by the liver and is a prominent protein found in the blood. It is a protein of a single polypeptide chain with a thiol group.

Applicazioni

Questa variante ricombinante è raccomandata per l'utilizzo nella ricerca farmacologica riguardo a assorbimento, distribuzione, metabolismo ed eliminazione (ADME); per le colture cellulari; per la ricerca sulla somministrazione di farmaci; e per la crioconservazione delle cellule.
Albumin human has been used:
  • to study its adsorption process on model mica surface at pH 3.5 using the atomic force microscopy (AFM) and in situ streaming potential measurements
  • to study its proteolytic activities under reducing conditions
  • in the medium for stem cell cultivation

Azioni biochim/fisiol

Albumin is a binding and transport protein that serves as a protein repository and a carrier for amino acids. Albumin binding dissolves the biomolecules in blood and ensures its effective transport. This also prevents the loss of substance through excretion. Pathological conditions like vasculitis, lymphangiectasia, glomerulonephritis, and hepatic sinusoidal hypertension might result in hypoalbuminemia. This product can be used in the pharmaceutical industry as a drug excipient and to coat medical devices.
Le albumine sono proteine monomeriche solubili presenti nei fluidi corporei, nei tessuti animali e nei semi di alcune piante. L'albumina sierica funziona come proteina carrier per steroidi, acidi grassi e ormoni tiroidei. Le albumine sieriche sono inoltre di vitale importanza nel regolare la pressione colloido-osmotica del sangue.

Risultati analitici

Endotoxin tested

Altre note

Visualizzare ulteriori informazioni sull′albumina sierica umana.

Codice della classe di stoccaggio

10 - Combustible liquids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable


Certificati d'analisi (COA)

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