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A5626

Sigma-Aldrich

Acetylthiocholine chloride

≥99% (TLC), powder

Sinonimo/i:

(2-Mercaptoethyl)trimethylammonium chloride acetate

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About This Item

Formula condensata:
CH3COSCH2CH2N(CH3)3Cl
Numero CAS:
6050-81-3
Peso molecolare:
197.73
Numero CE:
227-953-7
Numero MDL:
MFCD00038727
Codice UNSPSC:
12352204
ID PubChem:
24278219
NACRES:
NA.83

Livello qualitativo

200

Saggio

≥99% (TLC)

Forma fisica

powder

Solubilità

water: 100 mg/mL, clear to slightly hazy, colorless

Temperatura di conservazione

−20°C

Stringa SMILE

[Cl-].CC(=O)SCC[N+](C)(C)C

InChI

1S/C7H16NOS.ClH/c1-7(9)10-6-5-8(2,3)4;/h5-6H2,1-4H3;1H/q+1;/p-1
GZYVLKKMMDFCKR-UHFFFAOYSA-M

Informazioni sul gene

human ... ACHE(43)

Applicazioni

Acetylthiocholine chloride has been used to determine the acetylcholine esterase activity of semen exosomes (SE). It has also been used as a substrate for acetylcholine esterase in microcalorimetric study of its kinetic parameters.

Azioni biochim/fisiol

Acetylcholinesterase (AChE) enzyme plays an important physiological role in the neurotransmission process.
Acetylcholinesterase substrate and nicotinic acetylcholine receptor agonist.

Pittogrammi

Corrosion
GHS05

Avvertenze

Danger

Indicazioni di pericolo

H318

Classi di pericolo

Eye Dam. 1

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Certificati d'analisi (COA)

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Tanja Botić et al.
European journal of medicinal chemistry, 136, 294-304 (2017-05-16)
The brominated pyrroloiminoquinone alkaloids discorhabdins B, L and G and 3-dihydro-7,8- dehydrodiscorhabdin C, isolated from methanol extracts of two specimens of Latrunculia sp. sponges collected near the Antarctic Peninsula, are here demonstrated for the first time to be reversible competitive
Alexandra Raileanu et al.
Journal of nanoscience and nanotechnology, 18(10), 6905-6912 (2018-06-30)
Here we report on the fabrication and characterization of cluster-assembled nanostructured zirconia electrodes for the electrochemical detection of enzymatically produced thiocholine. Zirconia nanostructures are produced by Supersonic Cluster Beam Deposition on thin gold films. This technique enables nanoscale control of
Roberto M Maciel et al.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 84, 559-568 (2016-10-04)
The present study investigated the protective effect of quercetin (Querc) on memory, anxiety-like behavior and impairment of ectonucleotidases and acetylcholinesterase (AChE) activities in brain of streptozotocin-induced diabetic rats (STZ-diabetes). The type 1 diabetes mellitus was induced by an intraperitoneal injection
Lindon W K Moodie et al.
Organic & biomolecular chemistry, 14(47), 11220-11229 (2016-11-15)
The marine secondary metabolite stryphnusin (1) was isolated from the boreal sponge Stryphnus fortis, collected off the Norwegian coast. Given its resemblance to other natural acetylcholinesterase antagonists, it was evaluated against electric eel acetylcholinesterase and displayed inhibitory activity. A library
Nadin Aftim et al.
Talanta, 174, 414-419 (2017-07-26)
Molecularly imprinted polymers (MIPs) for phosmet insecticide were synthesized by batch polymerization. The affinity of functional monomers to phosmet was tested using an original method involving an electrochemical biosensor based on acetylcholinesterase inhibition. It was demonstrated that association of phosmet
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