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83695

Sigma-Aldrich

Rhodamine 110 chloride

suitable for fluorescence, BioReagent, ≥99.0% (UV)

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About This Item

Formula empirica (notazione di Hill):
C20H14N2O3 · HCl
Numero CAS:
13558-31-1
Peso molecolare:
366.80
Beilstein:
4631860
Numero CE:
236-944-7
Numero MDL:
MFCD00042009
Codice UNSPSC:
12171500
ID PubChem:
57652964
NACRES:
NA.32

Nome Commerciale

BioReagent

Saggio

≥99.0% (UV)

Forma fisica

crystals

Punto di fusione

>300 °C (lit.)

Solubilità

ethanol: soluble
methanol: soluble

Fluorescenza

λex 498 nm; λem 520 nm in methanol

Compatibilità

suitable for fluorescence

Stringa SMILE

Cl.Nc1ccc2c(OC3=CC(=N)C=CC3=C2c4ccccc4C(O)=O)c1

InChI

1S/C20H14N2O3.ClH/c21-11-5-7-15-17(9-11)25-18-10-12(22)6-8-16(18)19(15)13-3-1-2-4-14(13)20(23)24;/h1-10,21H,22H2,(H,23,24);1H
JNGRENQDBKMCCR-UHFFFAOYSA-N

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Descrizione generale

Rhodamine 110 or R110 is a triphenylmethane dye and emits a strong green-fluorescent light. The high fluorescence is attributed to the presence of amino groups as electron donating groups. Rhodamine 110 has excitation and emission maximum at 502.4/521.6 nm, respectively.

Applicazioni

Rhodamine 110 is used for the determination of protease activity with accurate kinetic parameters. It is used to measure caspase activity in cells with induced apoptosis.

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

Eyeshields, Gloves, type N95 (US)

Certificati d'analisi (COA)

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Xian Zhang et al.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 59(8), 1667-1672 (2003-05-09)
A simple and sensitive fluorescence quenching method for the determination of trace nitrite has been developed. The method is based on the reaction of Rhodamine 110 with nitrite in acidic medium to form a new compound, which has much lower
Melissa M Yatzeck et al.
Bioorganic & medicinal chemistry letters, 18(22), 5864-5866 (2008-07-04)
A derivative of rhodamine 110 has been designed and assessed as a probe for cytochrome P450 activity. This probe is the first to utilize a 'trimethyl lock' that is triggered by cleavage of an ether bond. In vitro, fluorescence was
Marcos M Pires et al.
Organic letters, 10(5), 837-840 (2008-02-09)
Glutathione is a crucial component of the redox homeostasis of cells, and altered levels have been linked to human pathologies. We constructed a latent fluorophore (RhoSS) that responds to cellular thiols in vitro and in cyto following intracellular reduction by
P-O Gendron et al.
Journal of fluorescence, 18(6), 1093-1101 (2008-04-24)
Rhodamine derivatives are popular, photostable fluorophores that are used in a number of fluorescent based techniques, including fluorescence correlation spectroscopy (FCS). Indeed, in FCS, both rhodamine 6G (R6G) and rhodamine 110 (R110) are used as calibration standards to determine the
Sambashiva Banala et al.
ACS chemical biology, 7(2), 289-293 (2011-10-27)
A caged rhodamine 110 derivative for the specific labeling of SNAP-tag fusion proteins is introduced. The caged rhodamine 110 derivative permits the labeling of cell surface proteins in living cells and of intracellular proteins in fixed cells. The probe requires
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