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Key Documents

75250

Sigma-Aldrich

Salvinorin B

≥93.0% (HPLC)

Sinonimo/i:

(2S,4aR,6aR,7R,9S,10aS,10bR)-2-(3-Furanyl)dodecahydro-9-hydroxy-6a,10b-dimethyl-4,10-dioxo 2H-naphtho[2,1-c]pyran-7-carboxylic acid methyl ester, Divinorin B

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About This Item

Formula empirica (notazione di Hill):
C21H26O7
Numero CAS:
Peso molecolare:
390.43
Beilstein:
4335292
Numero MDL:
Codice UNSPSC:
12352204
ID PubChem:
NACRES:
NA.83

Saggio

≥93.0% (HPLC)

Forma fisica

powder or crystals

Controllo stupefacenti

regulated under CDSA - not available from Sigma-Aldrich Canada

Solubilità

chloroform: soluble

Temperatura di conservazione

−20°C

Stringa SMILE

COC(=O)[C@@H]1C[C@H](O)C(=O)[C@H]2[C@@]1(C)CC[C@H]3C(=O)O[C@@H](C[C@]23C)c4ccoc4

InChI

1S/C21H26O7/c1-20-6-4-12-19(25)28-15(11-5-7-27-10-11)9-21(12,2)17(20)16(23)14(22)8-13(20)18(24)26-3/h5,7,10,12-15,17,22H,4,6,8-9H2,1-3H3/t12-,13-,14-,15-,17-,20-,21-/m0/s1
BLTMVAIOAAGYAR-CEFSSPBYSA-N

Azioni biochim/fisiol

Salvinorin B is the major deacetylated metabolite of salvinorin A, a diterpene from Salvia divinorum with reported psychotropic activity, not observed in Salvinorin B.

Confezionamento

Bottomless glass bottle. Contents are inside inserted fused cone.

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable


Certificati d'analisi (COA)

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Kai Yu et al.
Nature neuroscience, 20(12), 1680-1685 (2017-12-01)
Experience-driven synaptic plasticity in the lateral amygdala is thought to underlie the formation of associations between sensory stimuli and an ensuing threat. However, how the central amygdala participates in such a learning process remains unclear. Here we show that PKC-δ-expressing
Mark S Schmidt et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 818(2), 221-225 (2005-03-01)
Salvinorin A was quantitated in human and rhesus monkey plasma, rhesus monkey cerebrospinal fluid, and human urine by negative ion LC-MS/APCI. The method for Salvinorin A has been fully validated, the LLOQ using FDA guidelines is 2 ng/mL for 0.5
Thomas A Munro et al.
Bioorganic & medicinal chemistry, 16(3), 1279-1286 (2007-11-06)
Protection of salvinorin B as standard alkoxyalkyl ethers yielded highly potent kappa opioid receptor agonists. Ethoxymethyl ether 6 is among the most potent and selective kappa agonists reported to date. Fluoroethoxymethyl ether 11 is the first potent, selective fluorinated kappa
Seda Damla Hatipoglu et al.
Phytochemical analysis : PCA, 28(6), 541-549 (2017-07-20)
Salvia, an important and widely available member of Lamiaceae family. Although comparative analysis on secondary metabolites in several Salvia species from Turkey has been reported, their hallucinogenic chemicals have not been screened thoroughly. This study provides LC-MS/MS analysis of 40
Kenji Tsujikawa et al.
Forensic science international, 180(2-3), 105-109 (2008-09-05)
Two major salvinorins, salvinorin A (SalA) and salvinorin B (SalB), in three Salvia divinorum dried leaf products and nine of its "concentrated extract" products circulated in Japan were determined. These ingredients were extracted twice with acetonitrile and decolored with graphite

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