466R-1

SDHB (EP288) Rabbit Monoclonal Primary Antibody

• Sinonimo/i: Succinate dehydrogenase B
• Codice UNSPSC: 12352203

Proprietà

• Origine biologica: rabbit
• Livello qualitativo: 100; 500
• Coniugato: unconjugated
• Forma dell’anticorpo: culture supernatant
• Tipo di anticorpo: primary antibodies
• Clone: EP288, monoclonal
• Descrizione: For In Vitro Diagnostic Use in Select Regions
• Stato: buffered aqueous solution
• Reattività contro le specie: human
• Confezionamento: vial of 0.1 mL concentrate (466R-14); vial of 0.1 mL concentrate Research Use Only (466R-14-RUO); vial of 0.5 mL concentrate (466R-15); vial of 1.0 mL concentrate (466R-16); vial of 1.0 mL concentrate Research Use Only (466R-16-RUO); vial of 1.0 mL pre-dilute Research Use Only (466R-17-RUO); vial of 1.0 mL pre-dilute ready-to-use (466R-17); vial of 7.0 mL pre-dilute ready-to-use (466R-18); vial of 7.0 mL pre-dilute ready-to-use Research Use Only (466R-18-RUO)
• Produttore/marchio commerciale: Cell Marque^™
• tecniche: immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:25-1:100 (concentrated)
• Isotipo: IgG
• Controllo: GIST
• Condizioni di spedizione: wet ice
• Temperatura di conservazione: 2-8°C
• Visualizzazione: cytoplasmic
• Informazioni sul gene: human ... SDHB(6390)

Descrizione

Descrizione generale

Succinate dehydrogenase B (SDHB) is an iron-sulfur subunit of mitochondrial complex II, a respiratory complex that catalyzes the oxidation of succinate in the mitochondrial membrane. Many cancers are generally positive for SDHB, including renal cell carcinomas (RCC) and gastrointestinal stromal tumors (GIST). However, a subset of RCC and GIST tumors that are associated with SDH mutations, Carney-Stratakis Syndrome or Carney Triad exhibit a loss of SDHB expression.

Qualità

IVD

IVD

IVD

RUO

Stato fisico

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide.

Nota sulla preparazione

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Altre note

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

Note legali

Cell Marque is a trademark of Merck KGaA, Darmstadt, Germany

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 12 - Non Combustible Liquids
• Classe di pericolosità dell'acqua (WGK): WGK 2
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable