465R-1

TROP2 (EP431) Rabbit Monoclonal Primary Antibody

• Sinonimo/i: Trophoblast Antigen 2
• Codice UNSPSC: 12352203

Proprietà

• Origine biologica: rabbit
• Livello qualitativo: 100; 500
• Coniugato: unconjugated
• Forma dell’anticorpo: culture supernatant
• Tipo di anticorpo: primary antibodies
• Clone: EP431, monoclonal
• Descrizione: For In Vitro Diagnostic Use in Select Regions
• Stato: buffered aqueous solution
• Reattività contro le specie: human
• Confezionamento: vial of 0.1 mL concentrate (465R-14); vial of 0.1 mL concentrate Research Use Only (465R-14-RUO); vial of 0.5 mL concentrate (465R-15); vial of 1.0 mL concentrate (465R-16); vial of 1.0 mL concentrate Research Use Only (465R-16-RUO); vial of 1.0 mL pre-dilute Research Use Only (465R-17-RUO); vial of 1.0 mL pre-dilute ready-to-use (465R-17); vial of 7.0 mL pre-dilute ready-to-use (465R-18); vial of 7.0 mL pre-dilute ready-to-use Research Use Only (465R-18-RUO)
• Produttore/marchio commerciale: Cell Marque^®
• tecniche: immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:25-1:100 (concentrated)
• Isotipo: IgG
• Controllo: papillary carcinoma of thyroid
• Condizioni di spedizione: wet ice
• Temperatura di conservazione: 2-8°C
• Visualizzazione: cytoplasmic, membranous
• Informazioni sul gene: human ... TACSTD2(4070)

Descrizione

Descrizione generale

Trophoblast antigen 2 (TROP2) is a transmembrane glycoprotein that transduces intracellular calcium signals. The overexpression of TROP2 has been linked to tumor progression due to its involvement in the regulation of multiple vital cell processes including migration, proliferation, and invasion. TROP2 exhibits strong, diffuse staining in papillary thyroid carcinoma, while staining in other thyroid lesions, such as follicular thyroid adenomas and carcinomas, is limited to rare, focal, or scattered cells. An increase in TROP2 expression has also been observed in colorectal carcinomas and ovarian serous carcinomas compared to non-neoplastic ovary and colon.

Qualità

IVD

IVD

IVD

RUO

Stato fisico

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide.

Nota sulla preparazione

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Altre note

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

Note legali

Cell Marque is a registered trademark of Merck KGaA, Darmstadt, Germany

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 12 - Non Combustible Liquids
• Classe di pericolosità dell'acqua (WGK): WGK 2