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Key Documents

306M-2

Sigma-Aldrich

NSE (MRQ-55) Mouse Monoclonal Antibody

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About This Item

Codice UNSPSC:
12352203
NACRES:
NA.41

Origine biologica

mouse

Livello qualitativo

100
500

Coniugato

unconjugated

Forma dell’anticorpo

culture supernatant

Tipo di anticorpo

primary antibodies

Clone

MRQ-55, monoclonal

Descrizione

For In Vitro Diagnostic Use in Select Regions (See Chart)

Forma fisica

buffered aqueous solution

Reattività contro le specie

human

Confezionamento

vial of 0.1 mL concentrate (306M-24)
vial of 0.5 mL concentrate (306M-25)
bottle of 1.0 mL predilute (306M-27)
vial of 1.0 mL concentrate (306M-26)
bottle of 7.0 mL predilute (306M-28)

Produttore/marchio commerciale

Cell Marque™

tecniche

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:200

Isotipo

IgG2b

Controllo

appendix/colon, schwannoma

Condizioni di spedizione

wet ice

Temperatura di conservazione

2-8°C

Visualizzazione

cytoplasmic

Informazioni sul gene

human ... ENO2(2026)

Categorie correlate

Descrizione generale

Neuron-specific enolase (NSE) is a glycolytic isoenzyme of the enolase gamma-gamma dimerselectively detected in neurons, peripheral nerves, some neuroendocrine cells, and tumors.NSE immunoreactivity is also observed, to a lesser extent, in smooth muscle tissue. Anti-NSEis often used to visualize peripheral nerves and for the identification of neuroendocrinedifferentiation.

Qualità


IVD
IVD
IVD
RUO

Linkage

NSE Positive Control Slides, Product No. 306S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

Stato fisico

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

Nota sulla preparazione

Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.

Altre note

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

Note legali

Cell Marque is a trademark of Merck KGaA, Darmstadt, Germany

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Codice della classe di stoccaggio

12 - Non Combustible Liquids

Classe di pericolosità dell'acqua (WGK)

WGK 2

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Certificati d'analisi (COA)

Cerca il Certificati d'analisi (COA) digitando il numero di lotto/batch corrispondente. I numeri di lotto o di batch sono stampati sull'etichetta dei prodotti dopo la parola ‘Lotto’ o ‘Batch’.

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N Leonard et al.
Gut, 37(6), 763-765 (1995-12-01)
The pathogenesis of villous damage in coeliac disease is unknown. Change to the delicate neuromuscular core may be significant and this study stained various categories of coeliac disease and controls with neuron-specific enolase (NSE) to examine neurofilaments in the mucosa.
M R Wick et al.
American journal of clinical pathology, 79(6), 703-707 (1983-06-01)
In order to better define the use of neuron-specific enolase (NSE) as a marker for neuroendocrine neoplasms, we studied 11 thymic carcinoid tumors, three bronchial small-cell carcinomas (all with cutaneous metastases), and 10 trabecular carcinomas of the skin for its
A S Leong et al.
Pathology, 18(4), 393-399 (1986-10-01)
Thirteen cases of primary endocrine carcinoma of the skin (Merkel cell carcinoma) were reviewed with the aim of defining the morphological, immunohistochemical and ultrastructural criteria for diagnosis. The tumour cells were characterized by their scanty cytoplasm, generally small uniform nuclei
E H Cooper
The International journal of biological markers, 9(4), 205-210 (1994-10-01)
The clinical value of neuron-specific enolase as a marker is small cell lung cancer, neuroblastoma, melanoma and seminoma has been reviewed. The role of serum and cerebrospinal NSE in benign and malignant disease of the central nervous system is discussed.
S A Vinores et al.
Archives of pathology & laboratory medicine, 108(7), 536-540 (1984-07-01)
In normal conditions, neuron-specific enolase (NSE) is histochemically demonstrable only in neurons and cells of the amine precursor uptake and decarboxylation (APUD) system. This has been found not to be true for neoplastic cells. Several types of CNS tumors, including

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