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Merck
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Documenti fondamentali

275R-1

Sigma-Aldrich

Ki-67 (SP6) Rabbit Monoclonal Antibody

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About This Item

Codice UNSPSC:
12352203
NACRES:
NA.41

Origine biologica

rabbit

Livello qualitativo

100
500

Coniugato

unconjugated

Forma dell’anticorpo

culture supernatant

Tipo di anticorpo

primary antibodies

Clone

SP6, monoclonal

Descrizione

For In Vitro Diagnostic Use in Select Regions (See Chart)

Stato

buffered aqueous solution

Reattività contro le specie

human

Confezionamento

vial of 0.1 mL concentrate (275R-14)
vial of 0.5 mL concentrate (275R-15)
bottle of 1.0 mL predilute (275R-17)
vial of 1.0 mL concentrate (275R-16)
bottle of 7.0 mL predilute (275R-18)

Produttore/marchio commerciale

Cell Marque®

tecniche

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:100-1:500

Isotipo

IgG

Controllo

tonsil

Condizioni di spedizione

wet ice

Temperatura di conservazione

2-8°C

Visualizzazione

nuclear

Informazioni sul gene

human ... MKI67(4288)

Categorie correlate

Descrizione generale

The Ki-67 antigen is a nuclear, non-histone protein that is present in proliferatingcells. Though its specific role is largely postulated and still yet to be determined,Ki-67’s presence during cellular division makes it an excellent target for labeling rapidlygrowing malignancies. Given that its presence correlates with cell proliferation, theimmunohistochemical labeling of Ki-67 antigen may be useful in characterizing a lesion’sgrowth fraction.

Qualità


IVD
IVD
IVD
RUO

Linkage

Ki-67 Positive Control Slides, Product No. 275S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

Stato fisico

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

Nota sulla preparazione

Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.

Altre note

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

Note legali

Cell Marque is a registered trademark of Merck KGaA, Darmstadt, Germany

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Codice della classe di stoccaggio

12 - Non Combustible Liquids

Classe di pericolosità dell'acqua (WGK)

WGK 2

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

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Certificati d'analisi (COA)

Lot/Batch Number
1420502A-Z
1506501A-Z

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Swerdlow S, et al. WHO clarifications of tumours of hematopoietic and lymphoid tissues. 4th edition, 2008. P 220.
WHO Classification of Tumours of Haematopoietic and Lymphoid Tissue, 220-220 (2008)
P E McKeever et al.
Journal of neuropathology and experimental neurology, 57(10), 931-936 (1998-10-24)
The purpose of this study was to determine whether a relationship existed between MIB-1 labeling index (LI) percentages and survival in patients with grade II astrocytomas. From archival paraffin-embedded surgical specimens of 50 patients of the University of Michigan Medical
S W Coons et al.
Neurosurgery, 41(4), 878-884 (1997-10-08)
The prognostic significance of quantitative measurement of tumor proliferative activity was evaluated for oligodendroglial tumors. Ki-67/MIB-1 immunochemistry was used to measure proliferative activity in 81 oligodendrogliomas and oligoastrocytomas. The relationship among survival, proliferation, histological features, and clinical variables were evaluated
Ran Marciano et al.
Cancers, 11(2) (2019-02-02)
Tumor cells utilize glucose to fuel their anabolic needs, including rapid proliferation. However, due to defective vasculature and increased glucose uptake, tumor cells must overcome glucose deprivation. Accordingly, tumor cells depend on cellular pathways promoting survival under such conditions. Targeting
Carmen J Allegra et al.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 21(2), 241-250 (2003-01-15)
To define the value of thymidylate synthase (TS), Ki-67, and p53 as prognostic markers in patients with stage II and III colon carcinoma. We retrospectively analyzed the prognostic value of TS, Ki-67, and p53 in 706 patients with Dukes' B
Visualizza tutti i documenti correlati

Articoli

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Contenuto correlato

Diagnostic Immunohistochemistry Procedures

Diagnostic immunohistochemistry overview highlights its importance in cancer diagnosis and detecting infectious diseases in modern clinical pathology.

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