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Key Documents

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Y0000441

Didanosine impurity A,

European Pharmacopoeia (EP) Reference Standard

Sinonimo/i:

Hypoxanthine, 6-Hydroxypurine

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About This Item

Formula empirica (notazione di Hill):
C5H4N4O
Numero CAS:
68-94-0
Peso molecolare:
136.11
Beilstein:
5811
Numero MDL:
MFCD00005725
Codice UNSPSC:
41116107
ID PubChem:
329830958
NACRES:
NA.24

Grado

pharmaceutical primary standard

Famiglia di API

didanosine

Produttore/marchio commerciale

EDQM

Punto di fusione

>300 °C (lit.)

applicazioni

pharmaceutical (small molecule)

Formato

neat

Temperatura di conservazione

2-8°C

Stringa SMILE

O=C1NC=Nc2nc[nH]c12

InChI

1S/C5H4N4O/c10-5-3-4(7-1-6-3)8-2-9-5/h1-2H,(H2,6,7,8,9,10)
FDGQSTZJBFJUBT-UHFFFAOYSA-N

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Descrizione generale

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Applicazioni

Hypoxanthine is a nutrient additive for a variety of cell culture applications involving bacterial, parasite (Plasmodium falciparum) and animal cells. Hypoxanthine is a component of selection media used in hybridoma technologies.

Confezionamento

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Altre note

Sales restrictions may apply.

Prodotti correlati

N° Catalogo
Descrizione
Determinazione del prezzo

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

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Hypoxanthine as an indicator of hypoxia: its role in health and disease through free radical production.
O D Saugstad
Pediatric research, 23(2), 143-150 (1988-02-01)
Matthias M Heck et al.
European urology, 66(2), 222-229 (2013-03-08)
To determine the anatomic extent of pelvic lymph node dissection (PLND) in prostate cancer (PCa) patients at the time of radical prostatectomy (RP), knowledge about the topography of lymph node (LN) metastases is required. Because small-volume LN metastases may be
Chia-Tung Wu et al.
Cardiovascular research, 102(3), 487-496 (2014-03-07)
Fibroblasts, which play an important role in cardiac function/dysfunction, including arrhythmogenesis, have voltage-dependent (Kv) currents of unknown importance. Here, we assessed the differential expression of Kv currents between atrial and ventricular fibroblasts from control dogs and dogs with an atrial
Ian A Lewis et al.
PLoS genetics, 10(1), e1004085-e1004085 (2014-01-07)
Drug resistant strains of the malaria parasite, Plasmodium falciparum, have rendered chloroquine ineffective throughout much of the world. In parts of Africa and Asia, the coordinated shift from chloroquine to other drugs has resulted in the near disappearance of chloroquine-resistant
Katie May Slattery et al.
Medicine and science in sports and exercise, 46(6), 1114-1123 (2014-03-01)
This investigation examined the ergogenic effect of short-term oral N-acetylcysteine (NAC) supplementation and the associated changes in redox balance and inflammation during intense training. A double-blind randomized placebo-controlled crossover design was used to assess 9 d of oral NAC supplementation
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Articoli

HPLC Analysis of Xanthines on Purospher® STAR RP-18 endcapped

Xanthine is a purine base found in most human body tissues and fluids as well as in other organisms. Methylated xanthines (methylxanthines), which include caffeine, paraxanthine, theobromine, and theophylline, commonly used for their effects as mild stiµlants and as bronchodilators, notably in the treatment of asthma symptoms. This application shows the efficient separation of several common xanthines and may be applied their analysis in any number of desired matrices.

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