SMB00913

BAA485 (12-Ketodeoxycholic acid)

≥95% (HPLC)

• Sinonimo/i: BAA485 (12-Ketodeoxycholic acid), (3α,5β)-3-Hydroxy-12-oxocholan-24-oic acid, 12-Dehydrodeoxycholic acid, 12-Oxolithocholic acid, 3α-Hydroxy-12-oxo-5β-cholan-24-oic acid, 3α-Hydroxy-12-oxo-5β-cholanic acid
• Formula empirica (notazione di Hill): C₂₄H₃₈O₄
• Numero CAS: 5130-29-0
• Peso molecolare: 390.56
• Codice UNSPSC: 41141802
• NACRES: NA.25

Proprietà

• Saggio: ≥95% (HPLC)
• Forma fisica: powder
• Qualità: 100
• Composizione: (3α,5α)-3-Hydroxy-12-oxocholan-24-oic acid, ≤100%
• Confezionamento: pkg of 25 mg
• Colore: white to beige
• Punto di fusione: 165—167 °C
• Solubilità: methanol: 20 mg/mL
• Temperatura di conservazione: 2-8°C
• Stringa SMILE: C[C@H](CCC(O)=O)C1CC[C@@]([C@]21C)([H])[C@]3([H])CC[C@]4([H])C[C@H](O)CC[C@]4(C)[C@@]3([H])CC2=O
• InChI: 1S/C24H38O4/c1-14(4-9-22(27)28)18-7-8-19-17-6-5-15-12-16(25)10-11-23(15,2)20(17)13-21(26)24(18,19)3/h14-20,25H,4-13H2,1-3H3,(H,27,28)/t14-,15-,16-,17+,18-,19+,20+,23+,24-/m1/s1; CVNYHSDFZXHMMJ-VPUMZWJWSA-N

Descrizione

Descrizione generale

BAA485 (12-oxolithocholic acid) is a microbiome-produced derivative of deoxycholic acid and it is a potent activator of the Pyrin inflammasome. BAA485 induces secretion of IL18 in LPS-primed PBMCs.

Bile acids, natural steroid amphipathic compounds formed through cholesterol oxidation in the liver, play a crucial role in regulating lipid metabolism. They facilitate the digestion, absorption, and transport of lipids, lipid-soluble vitamins, and related molecules in the gastrointestinal tract. These bile acids also impact various aspects of cholesterol, glucose, and energy balance.

Applicazioni

BAA485 (12-oxolithocholic acid) finds application in metabolomics, biochemical and microbiome research.

Caratteristiche e vantaggi

• Can be used in Metabolomics and Biochemical research
• High-quality compound suitable for multiple research applications

Altre note

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Informazioni sulla sicurezza

• Pittogrammi: GHS07
• Avvertenze: Warning
• Indicazioni di pericolo: H302
• Consigli di prudenza: P301 + P312 + P330
• Classi di pericolo: Acute Tox. 4 Oral
• Codice della classe di stoccaggio: 11 - Combustible Solids
• Classe di pericolosità dell'acqua (WGK): WGK 1
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable