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Key Documents

PHR1389

Supelco

Propyphenazone

Pharmaceutical Secondary Standard; Certified Reference Material

Sinonimo/i:

4-Isopropylantipyrine, 1,2-Dihydro-1,5-dimethyl-4-(1-methylethyl)-2-phenyl-3H-pyrazol-3-one, 1,2-Dihydro-4-isopropyl-1,5-dimethyl-2-phenyl-3H-pyrazol-3-one, Isopropylphenazone, Propyphenazone

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About This Item

Formula empirica (notazione di Hill):
C14H18N2O
Numero CAS:
Peso molecolare:
230.31
Beilstein:
204533
Numero MDL:
Codice UNSPSC:
41116107
ID PubChem:
NACRES:
NA.24

Grado

certified reference material
pharmaceutical secondary standard

Livello qualitativo

agenzia

traceable to Ph. Eur. P3750000

Famiglia di API

propyphenazone 

CdA

current certificate can be downloaded

tecniche

HPLC: suitable
gas chromatography (GC): suitable

applicazioni

pharmaceutical (small molecule)

Formato

neat

Temperatura di conservazione

2-8°C

Stringa SMILE

O=C1C(C(C)C)=C(C)N(C)N1C2=CC=CC=C2

InChI

1S/C14H18N2O/c1-10(2)13-11(3)15(4)16(14(13)17)12-8-6-5-7-9-12/h5-10H,1-4H3
PXWLVJLKJGVOKE-UHFFFAOYSA-N

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Descrizione generale

Propyphenazone is a nonsteroidal drug exhibiting anti-inflammatory properties. It is widely used as a mild anesthetic medicine. It belongs to the pyrazolone class of compounds and has been posited to elicit an allergic or pseudo allergic reaction.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Applicazioni

Propyphenazone can be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by chromatographic and spectrophotometric techniques.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Risultati analitici

These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.

Altre note

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Nota a piè di pagina

To see an example of a Certificate of Analysis for this material enter LRAA1896 in the slot below. This is an example certificate only and may not be the lot that you receive.

Prodotti correlati

N° Catalogo
Descrizione
Determinazione del prezzo

Pittogrammi

Exclamation mark

Avvertenze

Warning

Indicazioni di pericolo

Classi di pericolo

Acute Tox. 4 Oral

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable


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Certificati d'analisi (COA)

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A rapid spectrophotometric method to resolve ternary mixtures of propyphenazone, caffeine, and acetaminophen in tablets
Ozgur MU, et al.
Monatshefte fur Chemie / Chemical Monthly, 133(2), 219-223 (2002)
High-performance Liquid Chromatographic Determination of Paracetamol, Propyphenazone, and Caffeine in Pharmaceutical Formulations
Delvadiya K, et al.
Indian Journal of Pharmaceutical Education and Research, 47(4), 65-72 (2014)
Derivative ratio spectra-zero crossing spectrophotometry and LC method applied to the quantitative determination of paracetamol, propyphenazone and caffeine in ternary mixtures
Dinc E, et al.
Journal of Pharmaceutical and Biomedical Analysis, 26(5-6), 769-778 (2001)
Simultaneous determination of paracetamol, caffeine and propyphenazone in ternary mixtures by micellar electrokinetic capillary chromatography
Emre D and Ozalt?n, Nuran
Journal of Chromatography. B, Biomedical Sciences and Applications, 847(2), 126-132 (2007)
Simultaneous quantitation of paracetamol, caffeine and propyphenazone by high-pressure liquid chromatography
Mamolo MG, et al.
Journal of Pharmaceutical and Biomedical Analysis, 3(2), 157-164 (1985)

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