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PHL82226

Cucurbitacin B

phyproof® Reference Substance

Sinonimo/i:

Amarine

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About This Item

Formula empirica (notazione di Hill):
C32H46O8
Numero CAS:
6199-67-3
Peso molecolare:
558.70
Codice UNSPSC:
41116107
NACRES:
NA.24

Grado

primary reference standard

Nome Commerciale

phyproof® Reference Substance

Saggio

≥90.0% (HPLC)

Produttore/marchio commerciale

PhytoLab

applicazioni

food and beverages

Formato

neat

Temperatura di conservazione

2-8°C

Stringa SMILE

O[C@H]1[C@@H]([C@@]2([C@]([C@H]3[C@]([C@@H]4C[C@@H](C(=O)C(C4=CC3)(C)C)O)(C(=O)C2)C)(C1)C)C)[C@](O)(C)C(=O)\C=C\C(OC(=O)C)(C)C

InChI

1S/C32H46O8/c1-17(33)40-27(2,3)13-12-23(36)32(9,39)25-21(35)15-29(6)22-11-10-18-19(14-20(34)26(38)28(18,4)5)31(22,8)24(37)16-30(25,29)7/h10,12-13,19-22,25,34-35,39H,11,14-16H2,1-9H3/b13-12+/t19-,20+,21-,22+,25+,29+,30-,31+,32+/m1/s1
IXQKXEUSCPEQRD-DKRGWESNSA-N

Descrizione generale

This substance is a primary reference substance with assigned absolute purity (considering chromatographic purity, water, residual solvents, inorganic impurities). The exact value can be found on the certificate. Produced by PhytoLab GmbH & Co. KG

Note legali

phyproof is a registered trademark of PhytoLab GmbH & Co. KG

Pittogrammi

Skull and crossbones
GHS06

Avvertenze

Danger

Indicazioni di pericolo

H300

Classi di pericolo

Acute Tox. 2 Oral

Codice della classe di stoccaggio

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

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Certificati d'analisi (COA)

Lot/Batch Number
64679
130626564
84934690
62619759

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Dinia R Dwijayanti et al.
Phytotherapy research : PTR, 34(6), 1338-1346 (2019-12-18)
Bitter melon (Momordica charantia L.) is a vegetable and has been used as traditional medicine. Recently, we reported that bitter melon fruit extracts and its ethyl acetate (EtOAc)-soluble fraction markedly suppressed the expression of proinflammatory genes, including the inducible nitric
Li Yang et al.
Basic & clinical pharmacology & toxicology, 127(5), 371-379 (2020-05-27)
The present study investigated the improving effect of cucurbitacin B on liver fibrosis induced by concanavalin A in mice and explored its possible mechanism. AST, ALT and TB were detected by kits. ELISA was performed to detect the levels of
Jiaxin Xu et al.
Archives of biochemistry and biophysics, 684, 108314-108314 (2020-02-24)
Signal transducer and activator of transcription 3 (STAT3) is expressed aberrantly in multiple tumors, including gastric cancer (GC). STAT3 overexpression and excessive activation have been confirmed to play vital roles in tumorigenesis. Cucurbitacin B (CuB) is a natural product with
Jiangxia Du et al.
Toxicology letters, 338, 1-9 (2020-11-29)
Gefitinib is an epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor indicated for the first-line treatment of patients with metastatic or advanced non-small cell lung cancer (NSCLC) whose tumors have specific EGFR mutations. Pulmonary toxicity is one of the fatal
Yuki Yoshida et al.
BMC developmental biology, 19(1), 24-24 (2019-12-23)
Tardigrades are microscopic organisms, famous for their tolerance against extreme environments. The establishment of rearing systems of multiple species has allowed for comparison of tardigrade physiology, in particular in embryogenesis. Interestingly, in-lab cultures of limnic species showed smaller variation in

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