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O0150000

Omeprazolo

European Pharmacopoeia (EP) Reference Standard

Sinonimo/i:

5-metossi-2-[[(4-metossi-3,5-dimetil-2-piridinil)metil]sulfinil]-1H-benzimidazolo, Antra, Losec

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About This Item

Formula empirica (notazione di Hill):
C17H19N3O3S
Numero CAS:
73590-58-6
Peso molecolare:
345.42
Numero MDL:
MFCD00083192
Codice UNSPSC:
41116107
ID PubChem:
329818823
NACRES:
NA.24

Grado

pharmaceutical primary standard

Famiglia di API

omeprazole

Produttore/marchio commerciale

EDQM

tecniche

HPLC: suitable
gas chromatography (GC): suitable

applicazioni

pharmaceutical (small molecule)

Formato

neat

Stringa SMILE

COc1ccc2[nH]c(nc2c1)S(=O)Cc3ncc(C)c(OC)c3C

InChI

1S/C17H19N3O3S/c1-10-8-18-15(11(2)16(10)23-4)9-24(21)17-19-13-6-5-12(22-3)7-14(13)20-17/h5-8H,9H2,1-4H3,(H,19,20)
SUBDBMMJDZJVOS-UHFFFAOYSA-N

Informazioni sul gene

human ... ATP4A(495) , ATP4B(496)

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Categorie correlate

Descrizione generale

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Applicazioni

Omeprazole EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Confezionamento

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Altre note

Sales restrictions may apply.

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Pittogrammi

Exclamation markEnvironment
GHS07,GHS09

Avvertenze

Warning

Indicazioni di pericolo

H302 - H317 - H411

Classi di pericolo

Acute Tox. 4 Oral - Aquatic Chronic 2 - Skin Sens. 1

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 2

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

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Certificati d'analisi (COA)

Lot/Batch Number

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Omeprazole Related Compound A United States Pharmacopeia (USP) Reference Standard

USP

1478516

Omeprazole Related Compound A

Aydin Seref Köksal et al.
Acta gastro-enterologica Belgica, 76(1), 34-37 (2013-05-09)
Bismuth-containing quadruple therapy given four times a day is effective in the first-line treatment of Helicobacter pylori. We aimed to investigate whether twice daily posology could eradicate H. pylori at a comparable rate in an area with a high prevalence
R P Myers et al.
The American journal of gastroenterology, 96(12), 3428-3431 (2002-01-05)
Omeprazole is a proton pump inhibitor that is used commonly in the treatment of acid-peptic disorders. Although omeprazole is generally well tolerated, serious adverse effects such as renal failure have been reported. Thus far, 17 cases of acute interstitial nephritis
Anju Nohria et al.
Journal of the American Heart Association, 3(1), e000609-e000609 (2014-01-07)
Inflammation is fundamental to the development of atherosclerosis. We examined the effect of anti-inflammatory doses of salicylate on endothelium-dependent vasodilation, a biomarker of cardiovascular risk, in a broad range of subjects. We performed a randomized, double-blind, placebo-controlled crossover trial evaluating
A proton-pump inhibitor expedition: the case histories of omeprazole and esomeprazole.
Lars Olbe et al.
Nature reviews. Drug discovery, 2(2), 132-139 (2003-02-04)
Kazuhiro Shiizaki et al.
Molecular pharmacology, 85(2), 279-289 (2013-11-23)
Omeprazole (OME) induces the expression of genes encoding drug-metabolizing enzymes, such as CYP1A1, via activation of the aryl hydrocarbon receptor (AhR) both in vivo and in vitro. However, the precise mechanism of OME-mediated AhR activation is still under investigation. While
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