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Documenti fondamentali

E1100000

Ergosterol

European Pharmacopoeia (EP) Reference Standard

Sinonimo/i:

3β-Hydroxy-5,7,22-ergostatriene, 5,7,22-Ergostatrien-3β-ol, Provitamin D2

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About This Item

Formula empirica (notazione di Hill):
C28H44O
Numero CAS:
Peso molecolare:
396.65
Beilstein:
2338604
Numero MDL:
Codice UNSPSC:
41116107
ID PubChem:
NACRES:
NA.24

Origine biologica

plant

Grado

pharmaceutical primary standard

agenzia

EP

Famiglia di API

ergosterol

Stato

solid

Produttore/marchio commerciale

EDQM

tecniche

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

Punto di fusione

156-158 °C (lit.)

applicazioni

pharmaceutical (small molecule)

Formato

neat

Temperatura di conservazione

−20°C

Stringa SMILE

[H][C@@]1(CC[C@@]2([H])C3=CC=C4C[C@@H](O)CC[C@]4(C)[C@@]3([H])CC[C@]12C)[C@H](C)\C=C\[C@H](C)C(C)C

InChI

1S/C28H44O/c1-18(2)19(3)7-8-20(4)24-11-12-25-23-10-9-21-17-22(29)13-15-27(21,5)26(23)14-16-28(24,25)6/h7-10,18-20,22,24-26,29H,11-17H2,1-6H3/b8-7+/t19-,20+,22-,24+,25-,26-,27-,28+/m0/s1
DNVPQKQSNYMLRS-APGDWVJJSA-N

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Descrizione generale

Ergosterol is a biological precursor of vitamin D2 found in cell membranes of fungi and some protists such as trypanosomes.
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Applicazioni

Ergosterol may be used as an analytical reference standard for the determination of the analyte in pharmaceutical formulations by liquid chromatography.

Confezionamento

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Altre note

Sales restrictions may apply.

Prodotti correlati

N° Catalogo
Descrizione
Determinazione del prezzo

Indicazioni di pericolo

Classi di pericolo

Aquatic Chronic 4

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable


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Sigma-Aldrich

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Sigma-Aldrich

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Colesterolo

Ergocalciferol
European Pharmacopoeia Commission and European Directorate for the Quality of Medicines & Healthcare
European pharmacopoeia, 54(12), 6604-6606 (201)
Analysis of ergosterol in single kernel and ground grain by gas chromatography- mass spectrometry
Dong Y, et al.
Journal of Agricultural and Food Chemistry, 54(12), 4121-4125 (2006)
Cetin Kadakal et al.
Critical reviews in food science and nutrition, 44(5), 349-351 (2004-11-16)
The poor precision of the "percentage of discarded fruits" and "Howard mold count" methods has increased the importance of ergosterol for the microbiological quality evaluation of tomato and tomato products. Ergosterol, a constituent of the cell wall of some important
Yong-Qiang Zhang et al.
Virulence, 1(6), 551-554 (2010-12-24)
Many antifungal drugs including the highly successful azoles target the fungal-specific sterol, ergosterol, yet the molecular identity of cellular pathways mediating antifungal activity remained obscure. A recent study on the requirement of ergosterol in vacuolar H+-ATPase (V-ATPase) function uncovered a
M E da Silva Ferreira et al.
Medical mycology, 43 Suppl 1, S313-S319 (2005-08-23)
The continuous use of triazoles can result in the development of drug resistance. Azole-resistant clinical isolates, spontaneous and induced mutants of Aspergillus fumigatus have been documented. The azoles block the ergosterol biosynthesis pathway by inhibiting the enzyme 14-alpha-demethylase, product of

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