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Merck
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Documenti fondamentali

B5899

Supelco

Buflomedil hydrochloride

analytical standard

Sinonimo/i:

4-(1-Pyrrolidinyl)-1-(2,4,6-trimethoxyphenyl)-1-butanone

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About This Item

Formula empirica (notazione di Hill):
C17H25NO4 · HCl
Numero CAS:
Peso molecolare:
343.85
Numero CE:
Numero MDL:
Codice UNSPSC:
41116107
ID PubChem:
NACRES:
NA.24

Grado

analytical standard

Livello qualitativo

tecniche

HPLC: suitable
gas chromatography (GC): suitable

applicazioni

forensics and toxicology
pharmaceutical (small molecule)
veterinary

Formato

neat

Stringa SMILE

Cl.COc1cc(OC)c(C(=O)CCCN2CCCC2)c(OC)c1

InChI

1S/C17H25NO4.ClH/c1-20-13-11-15(21-2)17(16(12-13)22-3)14(19)7-6-10-18-8-4-5-9-18;/h11-12H,4-10H2,1-3H3;1H
ZDPACSAHMZADFZ-UHFFFAOYSA-N

Informazioni sul gene

human ... EBP(10682)

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Descrizione generale

Buflomedil hydrochloride is a vasoactive agent. Its mode of action involves increasing the peripheral and cerebral blood flow in ischaemic tissues of patients, who are mostly affected with vascular diseases.

Applicazioni

Buflomedil hydrochloride may be used as an analytical standard for the determination of buflomedil in biological matrices using high-performance liquid chromatography technique. It may also be used as an analytical reference standard for the quantification of the analyte in pharmaceutical formulations and serum samples using electroanalytical and chromatographic techniques.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

Eyeshields, Gloves, type N95 (US)


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Certificati d'analisi (COA)

Lot/Batch Number

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Cutaneous granulomatous reaction from mesotherapy.
Gonca Gokdemir et al.
Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.], 35(2), 291-293 (2009-02-14)
D Tsantilas et al.
International angiology : a journal of the International Union of Angiology, 28(3), 170-174 (2009-01-29)
Our understanding of vascular pathophysiology has significantly improved during the past two decades. Patients with type 2 diabetes mellitus have an increased vascular risk and a series of modifiable risk factors play a crucial role in the atherosclerotic process. The
Wei Wang et al.
Yao xue xue bao = Acta pharmaceutica Sinica, 47(7), 934-940 (2012-09-21)
The microbial transformation of buflomedil by Cunninghamella blakesleana AS 3.153 was studied, as well as a microbial model which can be used to mimic metabolism of buflomedil in mammal was established. Experiments were conducted to screen the capabilities of four
Denise Salles Coelho da Mota et al.
Clinics (Sao Paulo, Brazil), 64(8), 797-802 (2009-08-20)
This study investigated the effects of buflomedil and pentoxifylline, both of which are used in reconstructive surgery of hamster skin flap microcirculation, and evaluated the skin flap survival rate by orthogonal polarization spectral imaging. Twenty-four adult male Syrian golden hamsters

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