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B1390

Supelco

Bisacodyl

analytical standard, for drug analysis

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About This Item

Formula empirica (notazione di Hill):
C22H19NO4
Numero CAS:
603-50-9
Peso molecolare:
361.39
Numero CE:
210-044-4
Numero MDL:
MFCD00038039
Codice UNSPSC:
41116107
ID PubChem:
329773183
NACRES:
NA.24

Grado

analytical standard, for drug analysis

Livello qualitativo

100

tecniche

HPLC: suitable
gas chromatography (GC): suitable

applicazioni

forensics and toxicology
pharmaceutical (small molecule)
veterinary

Formato

neat

Temperatura di conservazione

2-8°C

Stringa SMILE

CC(=O)Oc1ccc(cc1)C(c2ccc(OC(C)=O)cc2)c3ccccn3

InChI

1S/C22H19NO4/c1-15(24)26-19-10-6-17(7-11-19)22(21-5-3-4-14-23-21)18-8-12-20(13-9-18)27-16(2)25/h3-14,22H,1-2H3
KHOITXIGCFIULA-UHFFFAOYSA-N

Informazioni sul gene

human ... CHRM4(1132)

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Descrizione generale

Bisacodyl is a diphenylmethane derivative, mainly used as a stimulant laxative for treating constipation.

Applicazioni

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Pittogrammi

Exclamation mark
GHS07

Avvertenze

Warning

Indicazioni di pericolo

H315,H319,H335

Classi di pericolo

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Organi bersaglio

Respiratory system

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 1

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

dust mask type N95 (US), Eyeshields, Gloves

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Certificati d'analisi (COA)

Lot/Batch Number
104K1274V
104K1274
104K1274
094K1456
034H0816

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Sigma-Aldrich

D9684

Dextromethorphan hydrobromide

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Sigma-Aldrich

35915

Sodium dichloroisocyanurate dihydrate

Stephen Vanner et al.
Canadian journal of gastroenterology = Journal canadien de gastroenterologie, 25(12), 663-666 (2011-12-17)
Despite the wealth of research investigating bowel cleansing efficacy, there are very little data on the timing or frequency of bowel movements after each agent is ingested. To examine the effect of each component of a three-day combined sodium picosulphate⁄magnesium
Nobutomo Ikarashi et al.
American journal of physiology. Gastrointestinal and liver physiology, 301(5), G887-G895 (2011-08-27)
The purpose of this study was to investigate the role of aquaporin3 (AQP3) in the colon in the laxative effect of bisacodyl. After oral administration of bisacodyl to rats, AQP3, macrophages, cyclooxygenase 2 (COX2), and prostaglandin E(2) (PGE(2)) were examined
Nobutomo Ikarashi et al.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 45(1-2), 73-78 (2011-11-17)
Patients with severe constipation are treated with combinations of several different laxatives. The purpose of this study is to examine whether the concomitant use of different laxatives enhances the laxative effect, using an osmotic laxative, magnesium sulphate (MgSO₄), and a
Dina Kao et al.
Canadian journal of gastroenterology = Journal canadien de gastroenterologie, 25(12), 657-662 (2011-12-17)
The ideal bowel cleansing regimen for colonoscopy has yet to be determined. To compare the cleansing efficacy, and patient tolerability and safety of four bowel preparation regimens. A total of 834 patients undergoing outpatient colonoscopy were randomly assigned to one
L Rodriguez et al.
Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society, 24(11), 1023-e545-1023-e545 (2012-07-05)
Describe the association of internal anal sphincter (IAS) relaxation with colonic high- amplitude peristaltic contractions (HAPCs). Retrospective review of colon manometry tracings of children with constipation to determine the IAS relaxation characteristics associated with HAPC's (HAPC-IASR) events and compare them
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