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A1200000

Anhydrotetracycline hydrochloride

European Pharmacopoeia (EP) Reference Standard

Sinonimo/i:

(4S,4aS,12aS)-4-(Dimethylamino)-1,4,4a,5,12,12a-hexahydro-3,10,11,12a-tetrahydroxy-6-methyl-1,12-dioxo-2-naphthacenecarboxamide monohydrochloride

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About This Item

Formula empirica (notazione di Hill):
C22H22N2O7 · HCl
Numero CAS:
13803-65-1
Peso molecolare:
462.88
Beilstein:
4228856
Numero MDL:
MFCD00151453
Codice UNSPSC:
41116107
ID PubChem:
329770683
NACRES:
NA.24

Grado

pharmaceutical primary standard

agenzia

EP Reference Standard

Famiglia di API

tetracycline

Produttore/marchio commerciale

EDQM

applicazioni

pharmaceutical (small molecule)

Formato

neat

Temperatura di conservazione

2-8°C

Stringa SMILE

Cl[H].[H][C@@]12Cc3c(C)c4cccc(O)c4c(O)c3C(=O)[C@]1(O)C(=O)C(C(N)=O)=C(O)[C@H]2N(C)C

InChI

1S/C22H22N2O7.ClH/c1-8-9-5-4-6-12(25)13(9)17(26)14-10(8)7-11-16(24(2)3)18(27)15(21(23)30)20(29)22(11,31)19(14)28;/h4-6,11,16,25-27,31H,7H2,1-3H3,(H2,23,30);1H/t11-,16-,22-;/m0./s1
XBSQEFHDCDFNJU-WPJNXPDPSA-N

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Descrizione generale

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Applicazioni

Anhydrotetracycline hydrochloride EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Confezionamento

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Altre note

Sales restrictions may apply.

Prodotti correlati

N° Catalogo
Descrizione
Determinazione del prezzo

PHR1041

Tetracycline hydrochloride, Pharmaceutical Secondary Standard; Certified Reference Material

1236506

4-Epianhydrotetracycline hydrochloride, United States Pharmacopeia (USP) Reference Standard

E0400000

4-Epianhydrotetracycline hydrochloride, European Pharmacopoeia (EP) Reference Standard

E0600000

4-Epitetracycline hydrochloride, European Pharmacopoeia (EP) Reference Standard

T0600000

Tetracycline hydrochloride, European Pharmacopoeia (EP) Reference Standard

1651009

Tetracycline hydrochloride, United States Pharmacopeia (USP) Reference Standard

1237509

Epitetracycline hydrochloride, United States Pharmacopeia (USP) Reference Standard

PHR1691

4-Epianhydrotetracycline hydrochloride, Pharmaceutical Secondary Standard; Certified Reference Material

1035708

Anhydrotetracycline hydrochloride, United States Pharmacopeia (USP) Reference Standard

BP480

Tetracycline hydrochloride, British Pharmacopoeia (BP) Reference Standard

PHR3175

Anhydrotetracycline Hydrochloride, pharmaceutical secondary standard, certified reference material

Pittogrammi

Health hazardExclamation mark
GHS08,GHS07

Avvertenze

Danger

Indicazioni di pericolo

H302,H360D

Classi di pericolo

Acute Tox. 4 Oral - Repr. 1B

Codice della classe di stoccaggio

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

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Certificati d'analisi (COA)

Lot/Batch Number

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Jonathan W Kotula et al.
Proceedings of the National Academy of Sciences of the United States of America, 111(13), 4838-4843 (2014-03-19)
The mammalian gut is a dynamic community of symbiotic microbes that interact with the host to impact health, disease, and metabolism. We constructed engineered bacteria that survive in the mammalian gut and sense, remember, and report on their experiences. Based
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A novel reversed-phase HPLC method was developed and validated for the assay of tetracycline hydrochloride and the limit of 4-epianhydrotetracycline hydrochloride impurity in tetracycline hydrochloride commercial bulk and pharmaceutical products. The method employed L1 (3 µm, 150 × 4.6 mm) columns, a mobile phase
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Biochemistry, 53(50), 7990-7998 (2014-11-29)
Genes that render bacteria resistant to tetracycline-derived antibiotics are tightly regulated by repressors of the TetR family. In their physiologically relevant, magnesium-complexed form, tetracyclines induce allosteric rearrangements in the TetR homodimer, leading to its release from the promoter and derepression
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Fluorescent proteins are powerful reporters in biology, but most require O2 for chromophore maturation, making them inherently difficult to use in anaerobic bacteria. Clostridium difficile, a strict anaerobe with a genomic GC content of only 29%, is the leading cause

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