938785

Sodium tert-butoxide ChemBeads

• Sinonimo/i: NaOtBu, Sodium 2-methylpropan-2-olate, Sodium t-butoxide, Sodium tert-butanolate, Sodium tert-butylate
• Numero CAS: 865-48-5
• Numero MDL: MFCD00040575
• Codice UNSPSC: 12352100

Proprietà

• Stato: solid ()
• Livello qualitativo: 100
• Composizione: loading of base, 14-16 wt. %
• Stringa SMILE: [Na+].CC(C)(C)[O-]
• InChI: 1S/C4H9O.Na/c1-4(2,3)5;/h1-3H3;/q-1;+1; MFRIHAYPQRLWNB-UHFFFAOYSA-N

Descrizione

Applicazioni

Sodium tert-butoxide may be used as a safe and effective alternative to sodium hydride for the coupling of hydroxyethyl adenine with diethyl p-toluenesulfonyloxymethanephosphonate to form 9-[2-(diethylphosphonomethoxy)ethyl]adenine (diethyl-PMEA), which is a key intermediate to prepare adefovir dipivoxil.
It can also be used:
- To facilitate the coupling of aryl halides with benzene derivatives in the presence of 10-phenanthroline derivative.
- To activate first-row transition-metal pre-catalysts.
- As a base for the amination of aryl chlorides in the presence of a novel palladacyclic precatalyst.
For general uses, product is also available in powdered form (359270)

Caratteristiche e vantaggi

ChemBeads are chemical coated glass beads. ChemBeads offer improved flowability and chemical uniformity perfect for automated solid dispensing and high-throughput experimentation. The method of creating ChemBeads uses no other chemicals or surfactants allowing the user to accurately dispense sub-milligram amounts of chemical.

Informazioni sulla sicurezza

• Pittogrammi: GHS02,GHS05
• Avvertenze: Danger
• Indicazioni di pericolo: H228,H251,H314
• Consigli di prudenza: P210 - P235 - P260 - P280 - P303 + P361 + P353 - P305 + P351 + P338
• Classi di pericolo: Eye Dam. 1 - Flam. Sol. 1 - Self-heat. 1 - Skin Corr. 1B
• Rischi supp: EUH014
• Codice della classe di stoccaggio: 4.2 - Pyrophoric and self-heating hazardous materials
• Classe di pericolosità dell'acqua (WGK): WGK 3