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Key Documents

89067

Supelco

Corosolic acid

analytical standard

Sinonimo/i:

(2α,3β)-2,3-Dihydroxyurs-12-en-28-oic acid, 2α-Hydroxyursolic acid, Colosolic acid, Corsolic acid, Glucosol

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About This Item

Formula empirica (notazione di Hill):
C30H48O4
Numero CAS:
Peso molecolare:
472.70
Numero MDL:
Codice UNSPSC:
85151701
ID PubChem:
NACRES:
NA.24

Grado

analytical standard

Livello qualitativo

Saggio

≥85.0% (HPLC)

Durata

limited shelf life, expiry date on the label

tecniche

HPLC: suitable
gas chromatography (GC): suitable

applicazioni

food and beverages

Formato

neat

Stringa SMILE

O[C@H]1[C@H](O)C(C)(C)[C@@](CC[C@]2(C)[C@]3([H])CC=C4[C@@]2(C)CC[C@]5(C(O)=O)[C@@]4([H])[C@@H](C)[C@H](C)CC5)([H])[C@]3(C)C1

InChI

1S/C30H48O4/c1-17-10-13-30(25(33)34)15-14-28(6)19(23(30)18(17)2)8-9-22-27(5)16-20(31)24(32)26(3,4)21(27)11-12-29(22,28)7/h8,17-18,20-24,31-32H,9-16H2,1-7H3,(H,33,34)/t17-,18+,20-,21+,22-,23+,24+,27+,28-,29-,30+/m1/s1
HFGSQOYIOKBQOW-ZSDYHTTISA-N

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Categorie correlate

Applicazioni

Corosolic acid may be used as a reference standard in the determination of corosolic acid in Eriobotrya japonica leaves using reversed-phase high performance liquid chromatography (RP-HPLC).
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Azioni biochim/fisiol

Triterpene phytochemical found in medicinal herbal extracts. Possesses antiatherosclerotic, antihyperlipidemic, antioxidant, antiinflammatory, antifungal, antiviral and antineoplastic activities.

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable


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Certificati d'analisi (COA)

Lot/Batch Number

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Oleanolic acid ≥97%

Sigma-Aldrich

O5504

Oleanolic acid

Ganapathy Sivakumar et al.
Biotechnology journal, 4(12), 1704-1711 (2009-12-01)
Diabetes is one of the nation's most prevalent, debilitating and costly diseases. For diabetes, frequent insulin treatment is very expensive and may increase anti-insulin antibody production, which may cause unwanted side effects. Corosolic acid may also have some efficacy in
Baohong Li et al.
Pakistan journal of pharmaceutical sciences, 27(3), 511-516 (2014-05-09)
A sensitive and robust liquid chromatography-tandem mass spectrometry (LC-MS/MS) method was developed and validated for the determination of corosolic acid (CRA) in rat plasma. The plasma samples were prepared by a simple protein precipitation treatment. Chromatographic separation was performed on
Ke Wang et al.
Oncology reports, 39(6), 2777-2786 (2018-04-06)
Retinoblastoma (Rb) is the most frequent primary intraocular tumor usually diagnosed in infants and children, and current therapy for such disease is still limited. Corosolic acid (CA), an ursane-type pentacyclic triterpene, has been assessed as a promising anticancer agent with little impact
Sidney J Stohs et al.
Phytotherapy research : PTR, 26(3), 317-324 (2011-11-19)
Banaba (Lagerstroemia speciosa L.) extracts have been used for many years in folk medicine to treat diabetes, with the first published research study being reported in 1940. This review summarizes the current literature regarding banaba and its constituents. The hypoglycemic
Determination of corosolic acid in Eriobotrya japonica leaves by reversed-phase high performance liquid chromatography.
CH, et al.
Se Pu / Chinese Journal of Chromatography, 24(5), 492-494 (2006)

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