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Merck
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74777

Millipore

Astragaloside IV

>98.0%

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About This Item

Formula empirica (notazione di Hill):
C41H68O14
Numero CAS:
84687-43-4
Peso molecolare:
784.97
Numero MDL:
MFCD16036240
Codice UNSPSC:
41106200
ID PubChem:
329765850
NACRES:
NA.85

Livello qualitativo

100

Saggio

≥98.0% (TLC)
>98.0%

Forma fisica

powder

Punto di fusione

295-296 °C (lit.)

Stringa SMILE

CC(C)(O)[C@@H]1CC[C@@](C)(O1)[C@H]2[C@@H](O)C[C@@]3(C)[C@@H]4C[C@H](O[C@@H]5O[C@H](CO)[C@@H](O)[C@H](O)[C@H]5O)[C@H]6C(C)(C)[C@H](CC[C@@]67C[C@@]47CC[C@]23C)O[C@@H]8OC[C@@H](O)[C@H](O)[C@H]8O

InChI

1S/C41H68O14/c1-35(2)24(54-33-29(48)26(45)20(44)17-51-33)9-11-41-18-40(41)13-12-37(5)31(39(7)10-8-25(55-39)36(3,4)50)19(43)15-38(37,6)23(40)14-21(32(35)41)52-34-30(49)28(47)27(46)22(16-42)53-34/h19-34,42-50H,8-18H2,1-7H3/t19-,20+,21-,22+,23-,24-,25-,26-,27+,28-,29+,30+,31-,32-,33-,34+,37+,38-,39+,40-,41+/m0/s1
QMNWISYXSJWHRY-YLNUDOOFSA-N

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Azioni biochim/fisiol

Anti-inflammatory.

Altre note

Chemical constituent of Astragali radix

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

Eyeshields, Gloves, type N95 (US)

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Certificati d'analisi (COA)

Lot/Batch Number
BCCB3090
BCCB2207
BCBX5957
BCBS9602V
BCBR2507V

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Cycloastragenol phyproof® Reference Substance

PHL82509

Cycloastragenol

Aspalathin primary reference standard

03520585

Aspalathin

Aloe-emodin ≥95% (HPLC)

Sigma-Aldrich

A7687

Aloe-emodin

Piceatannol powder

Sigma-Aldrich

P0453

Piceatannol

Galangin autophagy inducing flavonoid

Sigma-Aldrich

282200

Galangin

Ginsenoside Rb1 European Pharmacopoeia (EP) Reference Standard

Y0001347

Ginsenoside Rb1

Fucoidan from Fucus vesiculosus ≥95%

Sigma-Aldrich

F8190

Fucoidan from Fucus vesiculosus

Dexin Li et al.
Pharmaceutical biology, 58(1), 89-97 (2020-01-08)
Context: Osteoarthritis (OA) is a degenerative arthrosis sickness. Astragaloside IV (AS-IV) functions by relieving inflammatory damage.Objective: We aimed to investigate the mechanism by which AS-IV protects ATD cells from lipopolysaccharide (LPS)-induced damage.Materials and methods: ATDC5 cells were transfected with miR-203
Dingkun Gui et al.
Cytokine, 61(3), 970-977 (2013-02-26)
Accumulating evidence suggests that inflammatory processes are involved in the development of diabetic nephropathy (DN). However, there are no effective interventions for inflammation in the diabetic kidneys. Here, we tested the hypothesis that Astragaloside IV(AS-IV), a novel saponin purified from
Mincai Li et al.
European journal of pharmacology, 696(1-3), 203-209 (2012-10-09)
Diabetic hyperglycemia causes a variety of pathological changes. Astragaloside IV (AS-IV) was widely used for the treatment of cardiovascular diseases in China. The aim of this study was to determine the effect of AS-IV on bone marrow mesenchymal stem cells
Yan-Xu Chang et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 911, 71-75 (2012-12-12)
According to Traditional Chinese Medicine (TCM) theories, TCM with different meridian tropism have different therapeutic effects. In view of the meridian tropism of Astragalus membranaceus (Huangqi), astragaloside IV, one of the effective phytochemicals of Huangqi, was appointed and observed its
Min Li et al.
Neurochemistry international, 60(5), 458-465 (2012-02-22)
Inflammation injury plays a key role in the process of cerebral injury induced by ischemia/reperfusion (I/R). Thus, we studied the potential of astragaloside IV, one of the major and active components of the astragalus membranaceous, to protect rat against cerebral
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