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Key Documents

67770

Millipore

Methyl α-D-mannopyranoside

≥99.0%, suitable for microbiology, enables differentiation between species of Listeria

Sinonimo/i:

Methyl alpha-D-mannoside, Methyl-alpha-D-mannopyranoside, α-Methyl D-mannoside

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About This Item

Formula empirica (notazione di Hill):
C7H14O6
Numero CAS:
Peso molecolare:
194.18
Beilstein:
81566
Numero CE:
Numero MDL:
Codice UNSPSC:
41106212
ID PubChem:
NACRES:
NA.85

Livello qualitativo

Saggio

≥99.0% (sum of enantiomers, HPLC)
≥99.0%

Forma fisica

powder

Attività ottica

[α]20/D 77.0 to 82.0°, c = 10% in H2O

PM

194.18 g/mol

Punto di fusione

187-195 °C
193-196 °C (lit.)

Solubilità

H2O: 0.1 g/mL, clear, colorless

applicazioni

microbiology

Stringa SMILE

CO[C@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@@H]1O

InChI

1S/C7H14O6/c1-12-7-6(11)5(10)4(9)3(2-8)13-7/h3-11H,2H2,1H3/t3-,4-,5+,6+,7+/m1/s1
HOVAGTYPODGVJG-VEIUFWFVSA-N

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Descrizione generale

Methyl α-D-mannopyranoside is a compound that belongs to the class of organic compounds known as o-glycosyl compounds. It is used for the differentiation of Listeria species, Listeria monocytogenes, Listeria innocua, and Listeria welshimeri can ferment the sugar, producing acid which can be identified using an appropriate pH indicator. It has been used to synthesize a series of tri- and tetrahydroxylated seven-membered imino sugars in a study that worked towards a stable Noeuromycin (glycosyl cation mimic that strongly inhibits glycosidases) analog with a D-manno configuration. It has also been used in a study to investigate the primary mannose-binding site of Pradimicin A. (antifungal agent)

Applicazioni

Methyl α-D-mannopyranoside can be used to identify different species of Listeria based on their ability to ferment the sugar.

Altre note

Unwanted binding of avidin to endogenous lectins

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

404.1 °F

Punto d’infiammabilità (°C)

206.74 °C

Dispositivi di protezione individuale

Eyeshields, Gloves, type N95 (US)


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Prevention of nonspecific binding of avidin.
R C Duhamel et al.
Methods in enzymology, 184, 201-207 (1990-01-01)
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A virtual screening approach was used to identify new glycomimetics. The National Cancer Institute Diversity Set was docked into the carbohydrate binding site of the lectin concanavalin A (ConA). The resulting poses were analyzed and 19 molecules were tested for
Su Yu et al.
BMC gastroenterology, 9, 58-58 (2009-07-25)
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Over the past 10 years we have been developing a multi-attribute analytical platform that allows for the preparation of milligram amounts of functional, high-pure, and stable Torpedo (muscle-type) nAChR detergent complexes for crystallization purpose. In the present work, we have

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