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Key Documents

25107

Sigma-Aldrich

Potassium citrate tribasic monohydrate

meets analytical specification of Ph. Eur., BP, FCC, E332, 99-100.5% (calc with ref. to anhyd. subst.)

Sinonimo/i:

Citric acid tripotassium salt, Tripotassium citrate

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About This Item

Formula condensata:
HOC(COOK)(CH2COOK)2 · H2O
Numero CAS:
Peso molecolare:
324.41
Beilstein:
3924344
Numero CE:
Numero MDL:
Codice UNSPSC:
12352300
ID PubChem:
NACRES:
NA.21

Livello qualitativo

Saggio

99-100.5% (calc with ref. to anhyd. subst.)

Forma fisica

powder or crystals

Qualità

meets analytical specification of Ph. Eur., BP, FCC, E332

Impurezze

≤0.0005% heavy metals (as Pb)
4-6% water (Karl Fischer)

Perdita

3-6 loss on drying, 180°C

pH

7-9 (20 °C, 5%)

Punto di fusione

275 °C (dec.) (lit.)

Solubilità

glycerol: soluble 1 gm in 2.5 ml
water: soluble 1 gm in 0.65 ml
alcohol: insoluble

Anioni in tracce

chloride (Cl-): ≤30 mg/kg
oxalate (as oxalic acid): ≤100 mg/kg
sulfate (SO42-): ≤50 mg/kg

Cationi in tracce

As: ≤1 mg/kg
Cu: ≤10 mg/kg
Fe: ≤10 mg/kg
Hg: ≤1 mg/kg
Na: ≤3000 mg/kg
Pb: ≤1 mg/kg
Zn: ≤10 mg/kg

Compatibilità

in accordance for appearance of solution
passes test for reaction against H2SO4

applicazioni

pharmaceutical (small molecule)

Stringa SMILE

O.[K+].[K+].[K+].OC(CC([O-])=O)(CC([O-])=O)C([O-])=O

InChI

1S/C6H8O7.3K.H2O/c7-3(8)1-6(13,5(11)12)2-4(9)10;;;;/h13H,1-2H2,(H,7,8)(H,9,10)(H,11,12);;;;1H2/q;3*+1;/p-3
PJAHUDTUZRZBKM-UHFFFAOYSA-K

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Categorie correlate

Applicazioni

Potassium citrate tribasic monohydrate has been used for preparing citrate-supplemented water for feeding the Car5A, Car5B, and DKO breeding pairs of mice. Citrate supplementation enhances the perinatal death in mice. It is a citrate-based salt used as a phase constituent for characterizing ionic-liquid-based aqueous biphasic systems (ABS) and as a buffering agent.

Azioni biochim/fisiol

Potassium citrate tribasic monohydrate is the potassium salt of citric acid. It enhances the bone density hence used in the treatment of osteoporosis. Additionally, it neutralizes the protein-induced metabolic acidosis.

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 1

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

Eyeshields, Gloves, type N95 (US)


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Acido citrico ACS reagent, ≥99.5%

Sigma-Aldrich

251275

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Good's buffers as a basis for developing self-buffering and biocompatible ionic liquids for biological research.
M. Taha, F. e Silva, M. V. Quental et al.
Green Chemistry (2014)
Julie Mardon et al.
The Journal of nutrition, 138(4), 718-724 (2008-03-22)
High dietary protein intake generates endogenous acid production, which may adversely affect bone health. Alkaline potassium citrate (Kcit)(2) may contribute to the neutralization of the protein-induced metabolic acidosis. We investigated the impact of 2 levels of protein intake and Kcit
Characterization of aqueous biphasic systems composed of ionic liquids and a citrate-based biodegradable salt.
Helena Passos
Biochemical Engineering Journal, 67, 68-76 (2012)
Antonia Fabris et al.
Clinical journal of the American Society of Nephrology : CJASN, 4(12), 1974-1979 (2009-10-08)
In medullary sponge kidney (MSK)-a common malformative renal condition in patients with calcium nephrolithiasis-hypercalciuria, incomplete distal renal tubular acidosis, and hypocitraturia are common. Clinical conditions with concomitant hypercalciuria and/or incomplete distal renal tubular acidosis are almost invariably associated with bone
Zeynep Yarbaşi et al.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 79(5), 1304-1307 (2011-06-07)
An EPR and optical studies of VO2+ doped potassium dihydrogen citrate (PDHC) single crystals have been carried out at room temperature. It crystallizes in triclinic symmetry with the unit cell dimensions: a=11.343Å, b=13.078Å, c=6.272Å, α=89.79°, β=94.36°, γ=104.2°. The angular variation

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