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Key Documents

03439

Sigma-Aldrich

N-Ethyldiisopropylamine solution

suitable for peptide synthesis, ~2 M in 1-methyl-2-pyrrolidinone

Sinonimo/i:

N,N-Diisopropylethylamine, DIPEA, Hünig’s base

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About This Item

Formula empirica (notazione di Hill):
C8H19N
Numero CAS:
Peso molecolare:
129.24
Beilstein:
4124745
Numero MDL:
Codice UNSPSC:
12352100
ID PubChem:
NACRES:
NA.21

Forma fisica

liquid

Livello qualitativo

Concentrazione

~2 M in 1-methyl-2-pyrrolidinone

Impurezze

≤0.2% water (KFT)

Indice di rifrazione

n20/D 1.454

applicazioni

peptide synthesis

Stringa SMILE

CCN(C(C)C)C(C)C

InChI

1S/C8H19N/c1-6-9(7(2)3)8(4)5/h7-8H,6H2,1-5H3
JGFZNNIVVJXRND-UHFFFAOYSA-N

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Descrizione generale

N-Ethyldiisopropylamine (EDIA) reacts with monoactivated Michael acceptors to afford symmetrical sulfones.

Applicazioni

N,N-Diisopropylethylamine (DIPEA), also known as Hünig′s base, is a sterically hindered amine. It is commonly employed as a base in peptide synthesis. Additionally, DIPEA is also used in the Pd-catalyzed cross-coupling reactions, which include Heck coupling and Sonagashira coupling reactions.

Avvertenze

Danger

Classi di pericolo

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Dam. 1 - Flam. Liq. 3 - Repr. 1B - Skin Irrit. 2 - STOT SE 3

Organi bersaglio

Respiratory system

Codice della classe di stoccaggio

3 - Flammable liquids

Classe di pericolosità dell'acqua (WGK)

WGK 2

Punto d’infiammabilità (°F)

73.4 °F

Punto d’infiammabilità (°C)

23 °C

Dispositivi di protezione individuale

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter


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