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Documenti fondamentali

01973

Supelco

4-Aminobenzoic acid

analytical standard

Sinonimo/i:

PABA, Vitamin Bx, Vitamin H1

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About This Item

Formula condensata:
H2NC6H4CO2H
Numero CAS:
Peso molecolare:
137.14
Beilstein:
471605
Numero CE:
Numero MDL:
Codice UNSPSC:
41116107
ID PubChem:
NACRES:
NA.24

Grado

analytical standard

Livello qualitativo

Saggio

≥98.0% (HPLC)

Durata

limited shelf life, expiry date on the label

tecniche

HPLC: suitable
gas chromatography (GC): suitable

Punto di fusione

186-188 °C
187-189 °C (lit.)

Densità

1.374 g/mL at 25 °C (lit.)

applicazioni

cleaning products
cosmetics
environmental
food and beverages
personal care

Formato

neat

Stringa SMILE

Nc1ccc(cc1)C(O)=O

InChI

1S/C7H7NO2/c8-6-3-1-5(2-4-6)7(9)10/h1-4H,8H2,(H,9,10)
ALYNCZNDIQEVRV-UHFFFAOYSA-N

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Applicazioni


  • 4-Aminobenzoic Acid (PABA) in Pharmaceutical Development: Recognized as a valuable biochemical research reagent, 4-aminobenzoic acid is extensively used in the synthesis of various pharmaceutical compounds. Its role as a building block in drug design is crucial for developing new therapeutic agents, particularly in the fields of dermatology and oncology (Clegg and Nichol, 2024).

  • UV Protection Research: PABA is renowned for its UV-absorbing properties, making it a key ingredient in sunscreen formulations. Ongoing research evaluates its efficacy and safety, ensuring optimal protection against UV radiation and its potential role in preventing skin cancer (Wang et al., 2024).

  • Enzyme Inhibitor Studies: As a nucleoside enzyme inhibitor, 4-aminobenzoic acid is pivotal in biochemical studies that explore the inhibition mechanisms of specific enzymes. These studies are fundamental for understanding disease pathways and developing enzyme-targeted therapies (Buch et al., 2024).

  • Vitamin B10 Research: Also known as Vitamin B10, PABA is studied for its role in human nutrition and its therapeutic effects, including in the management of fibrotic skin disorders and hair growth promotion. Research continues to uncover the broader health benefits of this compound (Berto et al., 2024).

  • High-Purity PABA for Laboratory Applications: In scientific research, high-purity 4-aminobenzoic acid is essential for conducting precise and controlled experiments, particularly in studies related to its pharmacological properties and its interaction with other biochemical substances in the body (Park et al., 2024).

Confezionamento

Bottomless glass bottle. Contents are inside inserted fused cone.

Altre note

Ion Mobility: TWCCSN2 value of 133.2 Å2 [M+H]+

The collision cross section (CCS) measurement was provided by Waters Corporation, using the SYNAPT XS mass spectrometer.
For a description and overview of how ion mobility enables the measurement of the CCS of an ion visit ims.waters.com.
Further information on the SYNAPT XS mass spectrometer can be found on the IMS microsite and product webpage.

TWCCS measurements are expected to be within 2% of this reference value.

P/N 01973 is part of the Waters Extractables & Leachables UNIFI scientific library which can be downloaded from Waters Marketplace.

Indicazioni di pericolo

Consigli di prudenza

Classi di pericolo

Aquatic Chronic 3

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 2

Punto d’infiammabilità (°F)

339.8 °F - closed cup

Punto d’infiammabilità (°C)

171 °C - closed cup


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We assessed the diagnostic capability of the bentiromide test using a high-pressure liquid-chromatography method to analyze p-aminobenzoic acid and its metabolites in plasma as an indirect measure of exocrine pancreatic function. Mean total amine concentration in pancreatic-insufficient subjects was significantly
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The bentiromide test was evaluated using plasma p-aminobenzoic acid as an indirect test of pancreatic insufficiency in young children between 2 months and 4 years of age. To determine the optimal test method, the following were examined: (a) the best

Protocolli

Separation of Uracil; p-Aminobenzoic acid; Acetylsalicylic acid; Dehydroacetic acid; Benzoic acid; Methyl paraben; 3-Fluorobenzoic acid

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