MABE268

Anti-Musashi-1 Antibody, clone 7B11.1

clone 7B11.1, from mouse

• Sinonimo/i: RNA-binding protein Musashi homolog 1
• Codice UNSPSC: 12352203
• eCl@ss: 32160702
• NACRES: NA.41
• Clone: 7B11.1, monoclonal
• application: IHC; WB
• Reattività contro le specie: rat, mouse, human
• tecniche: immunohistochemistry: suitable; western blot: suitable
• citations: 5

Proprietà

• Origine biologica: mouse
• Livello qualitativo: 100
• Forma dell’anticorpo: purified immunoglobulin
• Tipo di anticorpo: primary antibodies
• Clone: 7B11.1, monoclonal
• Reattività contro le specie: rat, mouse, human
• tecniche: immunohistochemistry: suitable; western blot: suitable
• Isotipo: IgG2aκ
• N° accesso NCBI: NP_002433
• N° accesso UniProt: O43347
• Condizioni di spedizione: wet ice
• modifica post-traduzionali bersaglio: unmodified
• Informazioni sul gene: human ... MSI1(4440)

Descrizione

Descrizione generale

In mammals, the Musashi family is important for cell fate determination, playing roles in maintenance of the stem-cell state, cellular differentiation, nuclear signaling and tumorigenesis. Musashi-1 (also known as Msi1), is selectivley expressed in neural progenitor cells, including neural stem cells. Outside the nervous system, Musashi-1 is a selective marker for intestinal stem or early lineage cells. Musashi-1 interacts with the Notch pathway during asymmetric cell division by binding the 3′ UTR of Numb. Numb is prevented from repressing Notch signaling when Musashi-1 is present.

Immunogeno

GST-tagged recombinant protein corresponding to human Musashi-1.

Applicazioni

Research Category
Epigenetics & Nuclear Function

Research Sub Category
Neural Stem Cells

Use Anti-Musashi-1 Antibody, clone 7B11.1 (Mouse Monoclonal Antibody) validated in WB, IHC to detect Musashi-1 also known as RNA-binding protein Musashi homolog 1.

Western Blot Analysis: A representative lot detected Musashi-1 in HEK293, NIH/3T3, and PC-12 cell lysate.

Immunohistochemistry Analysis: A 1:1,000 dilution of this antibody detected Musashi-1 in mouse cerebellum, normal mouse brain, and normal human pons tissue.

Qualità

Evaluated by Western Blot in mouse E17 spinal cord tissue lysate.

Western Blot Analysis: 1 µg/mL of this antibody detected Musashi-1 in 10 µg of mouse E17 spinal cord tissue lysate.

Descrizione del bersaglio

~39 kDa observed

Linkage

Replaces: 03-114; 04-1041

Stato fisico

Format: Purified

Protein G Purified

Purified mouse monoclonal IgG2aκ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Stoccaggio e stabilità

Stable for 1 year at 2-8°C from date of receipt.

Risultati analitici

Control
Mouse E17 spinal cord tissue lysate.

Altre note

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Esclusione di responsabilità

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 12 - Non Combustible Liquids
• Classe di pericolosità dell'acqua (WGK): WGK 1
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable