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Key Documents

MAB5778

Sigma-Aldrich

Anti-NMDAR2B Antibody, CT

ascites fluid, clone 1C6.5C4, Chemicon®

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About This Item

Codice UNSPSC:
12352203
eCl@ss:
32160702
NACRES:
NA.41

Origine biologica

mouse

Livello qualitativo

Forma dell’anticorpo

ascites fluid

Clone

1C6.5C4, monoclonal

Reattività contro le specie

human, rat, rabbit, mouse

Produttore/marchio commerciale

Chemicon®

tecniche

western blot: suitable

Isotipo

IgG1

N° accesso NCBI

N° accesso UniProt

Condizioni di spedizione

dry ice

modifica post-traduzionali bersaglio

unmodified

Specificità

NMDAR2B, C-terminal. By Western blot the antibody reacts with a band at ~170 kDa on rat brain lysate.

Immunogeno

Recombinant protein from rat NMDAR2B.

Applicazioni

Research Category
Neuroscience
Research Sub Category
Neurotransmitters & Receptors
This Anti-NMDAR2B Antibody, C-terminal is validated for use in WB for the detection of NMDAR2B.
Western blot: 1:100-1:1,000 on rat brain lysate.

Optimal working dilutions must be determined by end user.

Stato fisico

Ascites
Liquid ascites.

Stoccaggio e stabilità

6 months at -20°C from date of shipment

Note legali

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Esclusione di responsabilità

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Raccomandato

N° Catalogo
Descrizione
Determinazione del prezzo

Codice della classe di stoccaggio

10 - Combustible liquids

Classe di pericolosità dell'acqua (WGK)

WGK 1

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable


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GluN2B protein deficits in the left, but not the right, hippocampus in schizophrenia.
Geddes, AE; Huang, XF; Newell, KA
BMC Psychiatry null
Marie Lise Frandemiche et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 34(17), 6084-6097 (2014-04-25)
Tau is a microtubule-associated protein well known for its stabilization of microtubules in axons. Recently, it has emerged that tau participates in synaptic function as part of the molecular pathway leading to amyloid-beta (Aβ)-driven synaptotoxicity in the context of Alzheimer's
Matthew T Swulius et al.
The Journal of comparative neurology, 518(20), 4243-4260 (2010-09-30)
In this study, we used electron tomography as well as immunogold labeling to analyze the morphology and distribution of proteins within postsynaptic densities (PSDs) isolated from rats before birth (embryonic day 19) and at postnatal days 2, 21, and 60.
Wenhui Qu et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 40(50), 9552-9563 (2020-11-04)
Triggering receptor expressed on myeloid cells 2 (TREM2), a receptor exclusively expressed by microglia in the brain, modulates microglial immune homeostasis. Human genetic studies have shown that the loss-of-function mutations in TREM2 signaling are strongly associated with an elevated risk
D J Laurie et al.
Brain research. Molecular brain research, 51(1-2), 23-32 (1998-01-14)
Mouse monoclonal antibodies were raised against bacterially expressed protein sequences of the NR2A, NR2B, NR2C and NR2D subunits of the rat NMDA receptor. From immunoblots of rat brain proteins, the apparent molecular weights of these subunits were 165, 170, 135

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