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MAB5200

Sigma-Aldrich

Anti-Synaptotagmin I Antibody

Chemicon®, from mouse

Sinonimo/i:

p65, Syt1

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About This Item

Codice UNSPSC:
12352203
eCl@ss:
32160702
NACRES:
NA.41

Origine biologica

mouse

Livello qualitativo

100

Forma dell’anticorpo

purified immunoglobulin

Tipo di anticorpo

primary antibodies

Clone

monoclonal

Reattività contro le specie

frog, bovine, chicken, rabbit, rat, shark, mouse

Produttore/marchio commerciale

Chemicon®

tecniche

immunocytochemistry: suitable
immunoprecipitation (IP): suitable
western blot: suitable

Isotipo

IgG2a

N° accesso NCBI

NM_005639.1

N° accesso UniProt

P21579

Condizioni di spedizione

dry ice

modifica post-traduzionali bersaglio

unmodified

Informazioni sul gene

human ... SYT1(6857)

Specificità

Synaptotagmin 1, also known as p65. By Western blot MAB5200 reacts with a single protein with a molecular weight of approximately 65 kDa. MAB5200 has not been epitope mapped.

Immunogeno

Rat brain synaptotagmin.

Applicazioni

Research Category
Neuroscience
Research Sub Category
Synapse & Synaptic Biology
This Anti-Synaptotagmin I Antibody is validated for use in IP, WB, IC for the detection of Synaptotagmin I.
Western blot: 5 μg/mL (colormetric) Immunocytochemistry

Immunoprecipitation

Optimal working dilutions and protocols must be determined by the end user.

Stato fisico

Format: Purified
Purified immunoglobulin. Liquid in PBS with 50% glycerol and 0.09% sodium azide.

Stoccaggio e stabilità

Maintain at -20°C in undiluted aliquots up to 12 months.Avoid repeated freeze/thaw cycles.

Altre note

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Note legali

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Esclusione di responsabilità

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Codice della classe di stoccaggio

10 - Combustible liquids

Classe di pericolosità dell'acqua (WGK)

WGK 2

Certificati d'analisi (COA)

Cerca il Certificati d'analisi (COA) digitando il numero di lotto/batch corrispondente. I numeri di lotto o di batch sono stampati sull'etichetta dei prodotti dopo la parola ‘Lotto’ o ‘Batch’.

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M Shao et al.
Neuroscience, 161(4), 988-1007 (2009-04-21)
Vestibular compensation refers to the behavioral recovery after a unilateral peripheral vestibular lesion. In chickens, posture and balance deficits are present immediately following unilateral vestibular ganglionectomy (UVG). After three days, most operated chickens begin to recover, but severe deficits persist
B Marquèze et al.
Biochimie, 82(5), 409-420 (2000-06-24)
The aim of this review is to give a broad picture of what is actually known about the synaptotagmin family. Synaptotagmin I is an abundant synaptic vesicle and secretory granule protein in neurons and endocrine cells which plays a key
AMPA receptor subunit expression in chick vestibular nucleus neurons.
Anastas Popratiloff, Ya-Xian Wang, Jared Narvid, Ronald S Petralia, Christian Giaume et al.
Journal of Neuroscience Research null
Identification of a synaptic vesicle-specific membrane protein with a wide distribution in neuronal and neurosecretory tissue
Matthew, W D, et al
The Journal of cell biology, 91, 257-269 (1981)
M Shao et al.
Neuroscience, 223, 333-354 (2012-08-09)
Unilateral damage to the peripheral vestibular receptors precipitates a debilitating syndrome of oculomotor and balance deficits at rest, which extensively normalize during the first week after the lesion due to vestibular compensation. In vivo studies suggest that GABA(B) receptor activation
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