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Key Documents

MAB352

Sigma-Aldrich

Anti-Serotonin Antibody, clone YC5/45

culture supernatant, clone YC5/45, Chemicon®

Sinonimo/i:

5-HT

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About This Item

Codice UNSPSC:
12352203
eCl@ss:
32160702
NACRES:
NA.41

Origine biologica

rat

Livello qualitativo

Forma dell’anticorpo

culture supernatant

Tipo di anticorpo

primary antibodies

Clone

YC5/45, monoclonal

Reattività contro le specie

mouse, human, rat, lizard, rabbit, pig

Produttore/marchio commerciale

Chemicon®

tecniche

immunohistochemistry: suitable

Isotipo

IgG

Condizioni di spedizione

dry ice

modifica post-traduzionali bersaglio

unmodified

Informazioni sul gene

human ... HTR1A(3350)

Specificità

Recognizes the formaldehyde conjugate of serotonin. Without paraformaldehyde treatment, it cross-reacts in liquid phase with dopamine and tryptamine in hemagglutination tests. Shows no reactivity with catecholamine-containing neurons in formaldehyde fixed preparations. MAB352 reacts with serotonin in neurons and recognizes serotonergic sites in fixed tissue sections. By cell agglutination, no cross reactivity with 5-hydroxyindolacetic acid, GABA, noradrenaline, 5-hydroxytryptophan, carnosine or melatonin.

Immunogeno

Serotonin conjugated to BSA.

Applicazioni

Anti-Serotonin Antibody, clone YC5/45 is an antibody against Serotonin for use in IH.
Immunohistochemistry at 1:100-1:200 for formaldehyde fixed tissue.

Optimal working dilutions must be determined by the end user.
Research Category
Neuroscience
Research Sub Category
Neurotransmitters & Receptors

Stato fisico

Lyophilized Supernatant, preservative free.
Unpurified

Stoccaggio e stabilità

Lyophilized antibody can be kept at 2-8°C for up to 3 months and should be kept at -20°C for long term storage. Reconstitute with 100μL sterile DI water. Maintain at -20°C in undiluted aliquots for up to 12 months. Avoid repeated freeze-thaw cycles.

Risultati analitici

Control
Brain tissue

Altre note

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Note legali

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Esclusione di responsabilità

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Pittogrammi

Exclamation mark

Avvertenze

Warning

Indicazioni di pericolo

Classi di pericolo

Eye Irrit. 2 - Skin Irrit. 2

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 2


Certificati d'analisi (COA)

Cerca il Certificati d'analisi (COA) digitando il numero di lotto/batch corrispondente. I numeri di lotto o di batch sono stampati sull'etichetta dei prodotti dopo la parola ‘Lotto’ o ‘Batch’.

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Reciprocal connections between subdivisions of the dorsal raphe and the nuclear core of the locus coeruleus in the rat.
Myung-A Kim, Hyun S Lee, Beob Y Lee, Barry D Waterhouse
Brain Research null
M Costa et al.
Neuroscience, 7(2), 351-363 (1982-02-01)
Immunoreactive nerve cell bodies and fibres in the intestine have been examined using three antibody preparations raised against 5-hydroxytryptamine. Cross reactivity studies indicate that the substance localized was an hydroxylated indoleamine. In the guinea-pig small intestine, nerve cell bodies were
Retrograde study of projections from the tuberomammillary nucleus to the dorsal raphe and the locus coeruleus in the rat.
Hyun S Lee, Beob Y Lee, Barry D Waterhouse
Brain Research null
Organisation and chemical neuroanatomy of the African elephant (Loxodonta africana) olfactory bulb.
Ngwenya A, Patzke N, Ihunwo AO, Manger PR.
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Analysis of gene function in the zebrafish retina.
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Methods null

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