MAB3502-I

Anti-Angiotensin Converting Enzyme Antibody, clone 2E2

culture supernatant, clone 2E2, from mouse

• Sinonimo/i: Angiotensin-converting enzyme, ACE, Dipeptidyl carboxypeptidase I, Kininase II, CD143
• Codice UNSPSC: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Proprietà

• Origine biologica: mouse
• Livello qualitativo: 100
• Forma dell’anticorpo: culture supernatant
• Tipo di anticorpo: primary antibodies
• Clone: 2E2, monoclonal
• Reattività contro le specie: rat
• Reattività contro le specie (prevista in base all’omologia): human (immunogen homology)
• tecniche: western blot: suitable
• Isotipo: IgG1
• N° accesso NCBI: NP_000780
• N° accesso UniProt: P12821
• Condizioni di spedizione: wet ice
• modifica post-traduzionali bersaglio: unmodified
• Informazioni sul gene: human ... ACE(1636)

Descrizione

Descrizione generale

Angiotensin-converting enzyme (ACE) is a zinc-metallopeptidase belonging to the peptidase M2 family. It catalyzes the conversion of angiotensin I to angiotensin II and the degradation of bradykinin, which increases the vasoconstrictive effects of angiotensin. The Angiotensin-converting enzyme plays an important role in maintaining cardiac function and vascular tone. It is highly expressed in the heart, lung, kidney, gastrointestinal system, and prostate. Defects in the Angiotensin-converting may contribute cardiac disease; and renal tubular dysgenesis, a condition characterized by persistent fetal anuria and perinatal death.

Immunogeno

Human Angiotensin Converting Enzyme.

Applicazioni

Anti-Angiotensin Converting Enzyme Antibody, clone 2E2.

Qualità

Evaluated by Western Blot in rat Angiotensin Converting Enzyme.

Western Blot Analysis: A 1:2,000 dilution of this antibody detected rat Angiotensin Converting Enzyme in WB.

Descrizione del bersaglio

~180 kDa observed. The calculated molecular weight is 150 kDa; however, this protein is known to be glycolsylated.

Linkage

Replaces: MAB3502

Stato fisico

Mouse monoclonal IgG1 cultured supernatant without preservatives.

Risultati analitici

Control
Rat Angiotensin Converting Enzyme

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 10 - Combustible liquids
• Classe di pericolosità dell'acqua (WGK): WGK 1
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable